Short-term outcomes of ovarian vein embolization with adjunctive local sclerotherapy in patients with pelvic venous disorder and vulvar varicosities: a single-center retrospective experience - Report - MDSpire

Short-term outcomes of ovarian vein embolization with adjunctive local sclerotherapy in patients with pelvic venous disorder and vulvar varicosities: a single-center retrospective experience

  • By

  • Kai Zheng

  • Qiangqiang Nie

  • Bin Ni

  • Xixi Guo

  • Yuguang Yang

  • Peng Liu

  • Zhidong Ye

  • Bo Ma

  • Xueqiang Fan

  • June 24, 2026

  • 0 min

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Outcomes of Ovarian Vein Embolization Combined with Local Sclerotherapy

Overview

This study evaluates the short-term safety and clinical outcomes of ovarian vein embolization with adjunctive local sclerotherapy in women with pelvic venous disorder and vulvar varicosities.

Background

Pelvic venous disorder (PeVD) is a common condition in women that can lead to chronic pain and varicosities. Vulvar varicosities are a significant manifestation of PeVD, and their treatment is often overlooked. This study addresses the integration of ovarian vein embolization and local sclerotherapy as a potential treatment strategy for this specific subgroup.

Data Highlights

MeasureBefore TreatmentAt Follow-Up
Mean VAS5.8 ± 1.80.9 ± 0.9
Mean PVCSS10.7 ± 2.34.0 ± 1.6
Complete Symptom ReliefN/A9 patients (56%)
Partial Symptom ReliefN/A7 patients (44%)

Key Findings

  • Technical success was achieved in all 16 patients treated.
  • Mean VAS score decreased significantly from 5.8 to 0.9.
  • Mean PVCSS decreased from 10.7 to 4.0.
  • Complete symptom relief was observed in 56% of patients.
  • No major procedure-related adverse events were reported.

Clinical Implications

The findings indicate that ovarian vein embolization combined with local sclerotherapy may be a treatment option for women with pelvic venous disorder and vulvar varicosities.

Conclusion

Ovarian vein embolization with adjunctive local sclerotherapy was associated with short-term symptom improvement in women with pelvic venous disorder and vulvar varicosities.

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  6. Frontiers in Surgery — Ultrasound-guided foam sclerotherapy vs. open surgical ligation for incompetent perforator veins: a retrospective cohort study
  7. The Society of Interventional Radiology Practice Guidance Document on Venous-Origin Chronic Pelvic Pain in Women
  8. Efficacy of embolotherapy for the treatment of pelvic congestion syndrome: A systematic review
  9. Pelvic Venous Disorders in Women: 5-Year Update from a Society of Interventional Radiology Foundation-Sponsored Research Consensus Panel - PubMed
  10. Effectiveness and safety of coils plus glue in slope embankment technology versus coils plus sclerosant in embolization therapy for reflux-type pelvic venous disorders - ScienceDirect
  11. Management of Extra-Pelvic Varicose Veins of Pelvic Origin in Female Patients
  12. The 2023 Society for Vascular Surgery, American Venous Forum, and American Vein and Lymphatic Society clinical practice guidelines for the management of varicose veins of the lower extremities. Part II: Endorsed by the Society of Interventional Radiology and the Society for Vascular Medicine - PMC

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