Clinical Case: Diagnosis of an Intramedullary Solitary Fibrous Tumor

Overview

This report details a rare case of an intramedullary solitary fibrous tumor diagnosed at the C7-T1 region in a man in his early 60s. The tumor was managed through maximal safe resection, with follow-up at 18 months.

Background

Intramedullary solitary fibrous tumors are exceptionally rare neoplasms of the central nervous system, often presenting with non-specific symptoms that complicate diagnosis. Accurate identification typically relies on histopathological examination and immunohistochemistry, particularly the detection of nuclear STAT6 expression.

Data Highlights

No numerical or trial data available.

Key Findings

• A 60-year-old male presented with over 7 years of progressive bilateral lower-extremity numbness.
• Magnetic resonance imaging revealed an enhancing intramedullary lesion at the C7-T1 level.
• The patient underwent gross total resection via posterior C7-T2 laminectomy with intraoperative monitoring.
• Histology confirmed a CNS WHO grade 1 solitary fibrous tumor with low mitotic activity.
• Postoperative follow-up at 18 months showed no recurrence.

Clinical Implications

The case highlights the importance of thorough histopathological evaluation and the role of STAT6 immunohistochemistry in diagnosing solitary fibrous tumors.

Conclusion

This case demonstrates the rarity and diagnostic challenges of intramedullary solitary fibrous tumors.

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