GLP-1 receptor agonists and psychiatric outcomes: a bibliometric analysis of research trends, thematic evolution, and collaboration networks - Report - MDSpire
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Analysis of Research Trends and Collaborative Networks in GLP-1 Receptor Agonists and Their Impact on Psychiatric Outcomes
Clinical Report: Analysis of Research Trends in GLP-1 Receptor Agonists
Background
The exploration of GLP-1 RAs has expanded due to their clinical success. Understanding the research landscape is crucial for identifying gaps and guiding future studies, especially as regulatory scrutiny increases. This bibliometric analysis aims to characterize publication trends and thematic evolution in this interdisciplinary field.
Data Highlights
Year
Number of Publications
Before 2004
Less than 10
2026
Nearly 500
Key Findings
Annual output of GLP-1 RA publications rose from fewer than 10 before 2004 to nearly 500 in 2026.
The research corpus included 1,063 journals, 9,269 authors, and 85 countries.
Depression research emerged as a distinct theme only between 2022 and 2026.
Thematic mapping indicated depression as a niche theme with high density but low centrality.
Clinical Implications
The findings highlight the need for further research integrating psychiatric outcomes in cardiometabolic trials involving GLP-1 RAs. Understanding the evolving landscape can inform clinicians about the potential psychiatric effects of these therapies.
Conclusion
This bibliometric analysis reveals significant growth in GLP-1 RA research, particularly concerning psychiatric outcomes, emphasizing the importance of continued exploration in this area.
by Maria Meritxell Roca Mora, Marcia Sanchez-Monge, Dibe Balardini Ayoub, Ana Beatriz P. Aguiar-Barros, Sofia Serrano-Porras, Renato de Filippis, Georgios Schoretsanitis
