Spinal metastases in geriatric patients: a retrospective single-center comparison of mortality and surgical outcomes following neurosurgical treatment - Report - MDSpire
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Spinal metastases in geriatric patients: a retrospective single-center comparison of mortality and surgical outcomes following neurosurgical treatment
Outcomes of Surgical Treatment for Spinal Metastases in Older Adults
Overview
This study evaluates postoperative outcomes in geriatric versus non-geriatric patients undergoing surgical treatment for spinal metastases. Geriatric patients showed a higher comorbidity burden, and median overall survival was lower in the geriatric cohort.
Background
Spinal metastases are prevalent in patients with systemic cancer and can significantly impact quality of life. Understanding the safety and efficacy of surgical interventions in older adults is crucial. This study aims to address gaps in knowledge regarding outcomes and complications associated with surgical treatment in this demographic.
Data Highlights
Age Group
Median Overall Survival (months)
p-value
< 70 years
12.0
0.026
≥ 70 years
10.5
Key Findings
Geriatric patients had a higher preoperative comorbidity burden and lower functional status.
No significant differences in early postoperative complications, readmission rates, or local tumor recurrence between age groups.
Independent factors associated with increased 1-year mortality in geriatric patients included obesity, surgical stabilization, and early surgical complications.
Median overall survival was significantly lower in geriatric patients compared to non-geriatric patients.
Preoperative Karnofsky Performance Scale < 70% was linked to higher mortality risk.
Clinical Implications
Understanding the specific risks associated with comorbidities can guide clinical decision-making.
Conclusion
The findings indicate that while geriatric patients do not experience worse early postoperative outcomes, they have a lower median survival.
by Saif-Eldin Abedellatif, Marija Janjic, Logman Khalafov, Harun Asoglu, Juliane Dittmer, Haitham Alenezi, Ivan Maiseyeu, Mohammed Jaber, Muriel Heimann, Tim Lampmann, Matthias Schneider, Hartmut Vatter, Motaz Hamed, Mohammed Banat