Spinal metastases in geriatric patients: a retrospective single-center comparison of mortality and surgical outcomes following neurosurgical treatment - Report - MDSpire

Spinal metastases in geriatric patients: a retrospective single-center comparison of mortality and surgical outcomes following neurosurgical treatment

  • By

  • Saif-Eldin Abedellatif

  • Marija Janjic

  • Logman Khalafov

  • Harun Asoglu

  • Juliane Dittmer

  • Haitham Alenezi

  • Ivan Maiseyeu

  • Mohammed Jaber

  • Muriel Heimann

  • Tim Lampmann

  • Matthias Schneider

  • Hartmut Vatter

  • Motaz Hamed

  • Mohammed Banat

  • July 16, 2026

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Outcomes of Surgical Treatment for Spinal Metastases in Older Adults

Overview

This study evaluates postoperative outcomes in geriatric versus non-geriatric patients undergoing surgical treatment for spinal metastases. Geriatric patients showed a higher comorbidity burden, and median overall survival was lower in the geriatric cohort.

Background

Spinal metastases are prevalent in patients with systemic cancer and can significantly impact quality of life. Understanding the safety and efficacy of surgical interventions in older adults is crucial. This study aims to address gaps in knowledge regarding outcomes and complications associated with surgical treatment in this demographic.

Data Highlights

Age GroupMedian Overall Survival (months)p-value
< 70 years12.00.026
≥ 70 years10.5

Key Findings

  • Geriatric patients had a higher preoperative comorbidity burden and lower functional status.
  • No significant differences in early postoperative complications, readmission rates, or local tumor recurrence between age groups.
  • Independent factors associated with increased 1-year mortality in geriatric patients included obesity, surgical stabilization, and early surgical complications.
  • Median overall survival was significantly lower in geriatric patients compared to non-geriatric patients.
  • Preoperative Karnofsky Performance Scale < 70% was linked to higher mortality risk.

Clinical Implications

Understanding the specific risks associated with comorbidities can guide clinical decision-making.

Conclusion

The findings indicate that while geriatric patients do not experience worse early postoperative outcomes, they have a lower median survival.

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  4. Recommendations | Spinal metastases and metastatic spinal cord compression | Guidance | NICE, 2023
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  6. Journal of Neuro-Oncology — Evaluating Factors Beyond Surgical Intervention in Intramedullary Spinal Cord Metastases: The Role of Neurological Function and Systemic Disease in Patient Outcomes
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  8. AO Spine Clinical Practice Recommendations: Reducing the Surgical Footprint of Surgery for Spinal Metastases - PMC
  9. Direct decompressive surgical resection in the treatment of spinal cord compression caused by metastatic cancer: a randomised trial - PubMed
  10. Perioperative outcomes after minimally invasive and open surgery for treatment of spine metastases: a systematic review and meta-analysis - PubMed
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