Indian Delphi consensus on cardiovascular risk mitigation in prostate cancer management - Report - MDSpire

Indian Delphi consensus on cardiovascular risk mitigation in prostate cancer management

  • By

  • Ganesh Bakshi

  • Alexander Lyon

  • Amit Joshi

  • Vivek Agarwala

  • S. K. Raghunath

  • Sanjai Kumar Addla

  • Rajesh Taneja

  • Anil Mandani

  • Bhalchandra Kashyapi

  • Saurabh Bhargava

  • Rakesh Sharma

  • Vinayak Agrawal

  • Ravi Nagar

  • R. Srivathsan

  • Keval Patel

  • Raj Patel

  • Hetan Shah

  • Allen Lai

  • Apurba Mukherjee

  • Sudhanshu Pandey

  • Aashishsingh Rajput

  • July 16, 2026

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Clinical Report: Consensus from Indian Experts on Reducing Cardiovascular Risks in the Management of Prostate Cancer

Background

Prostate cancer is increasingly prevalent in India, particularly among older men, with many presenting at advanced stages. Concurrently, cardiovascular disease is a leading cause of non-cancer mortality in this population.

Data Highlights

No numerical data provided in the source material.

Key Findings

  • The PCCV Risk Expert Panel recommends comprehensive baseline lifestyle and cardiometabolic assessments for prostate cancer patients.
  • Patients should be stratified into low, intermediate, or high cardiovascular risk categories.
  • GnRH antagonists are preferred for high-risk patients, with referrals to cardiologists for those at intermediate or high risk.
  • Ongoing cardiometabolic monitoring and lifestyle interventions are essential components of care.
  • The ABCDE framework (Awareness, Blood Pressure, Cholesterol/Cigarettes, Diet/Diabetes, Exercise) should be integrated into patient management.
  • A multidisciplinary care model involving oncologists, urologists, cardiologists, and primary care providers is recommended.

Clinical Implications

Coordination among specialists is crucial to manage the risks associated with treatment.

Conclusion

The expert consensus emphasizes proactive cardiovascular risk management in prostate cancer care.

Related Resources & Content

  1. APMA PCCV Expert Group, Springer, 2024 -- Evaluation of Cardiovascular Disease Risk and Integrated Care Approaches in Prostate Cancer Management with Androgen Deprivation Therapy
  2. The ASCO Post — Is a Diet Higher in Plant-Based Foods Associated With a Lower Risk of Prostate Cancer Progression and Recurrence?
  3. The ASCO Post — PSA—It Just Keeps Getting Better, So Why Should It Stand Alone?
  4. The ASCO Post — Plant-Based Diet May Offer Benefit in Patients With Prostate Cancer
  5. NCCN Prostate Cancer Guidelines
  6. EAU Guidelines on Prostate Cancer
  7. Cardiovascular Considerations During Cancer Therapy
  8. Cardiovascular Events in Prostate Cancer Treated With Novel ARSI
  9. Cardiovascular events among men with prostate cancer treated with androgen receptor signaling inhibitors: a systematic review, meta-analysis, and network meta-analysis | Prostate Cancer and Prostatic Diseases
  10. Cardiovascular Safety of Degarelix Versus Leuprolide in Patients With Prostate Cancer: The Primary Results of the PRONOUNCE Randomized Trial - PubMed
  11. RISK OF CARDIOVASCULAR DISEASE FOLLOWING DEGARELIX VERSUS GONADOTROPIN RELEASING HORMONE (GNRH) AGONISTS IN PATIENTS WITH PROSTATE CANCER: A SYSTEMATIC REVIEW AND META-ANALYSIS | JACC

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