Relationship Between Intraocular Pressure and Ocular Characteristics in Chinese Junior High Students Aged 14 to 18: Findings from the Anyang Childhood Eye Study - Report - MDSpire
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Relationship Between Intraocular Pressure and Ocular Characteristics in Chinese Junior High Students Aged 14 to 18: Findings from the Anyang Childhood Eye Study

  • By

  • Wei Si

  • Xiaoyuan Yang

  • Su Xu

  • He Li

  • Yongfang Tu

  • Yongjun Huo

  • Mengtian Kang

  • Ningli Wang

  • Shi-Ming Li

  • January 7, 2026

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Relationship Between Intraocular Pressure and Ocular Characteristics in Chinese Adolescents

Overview

This study investigated intraocular pressure (IOP) and its association with ocular parameters in 1,720 Chinese junior high students aged 14 to 18. Findings revealed no significant sex differences in IOP but identified correlations between IOP and ocular characteristics such as central corneal thickness, axial length, and refractive error.

Background

Intraocular pressure is vital for ocular health and is linked to diseases like glaucoma. Prior studies have focused mainly on adults, with limited data on adolescents, especially in East Asia where myopia prevalence is high. Understanding IOP's relationship with ocular features in this population may clarify its role in myopia progression and inform targeted interventions. This study addresses these gaps by analyzing IOP alongside ocular parameters in Chinese junior high students.

Data Highlights

ParameterMean ± SD
Age (years)15.93 ± 5.69
IOP Right Eye (mmHg)15.83 ± 3.11
IOP Left Eye (mmHg)15.98 ± 3.02
Central Corneal Thickness (μm)549.93 ± 32.69
Anterior Chamber Depth (mm)3.19 ± 0.24
Axial Length (mm)24.61 ± 1.17
Corneal Curvature (D)43.32 ± 1.46

Key Findings

  • No significant difference in IOP between male and female students was observed.
  • Mean IOP was approximately 15.8 mmHg in the right eye and 16.0 mmHg in the left eye.
  • Ocular parameters such as central corneal thickness, axial length, and anterior chamber depth were measured and showed expected variations.
  • Refractive error categories were defined, with myopia classified as SE < -0.5D, and further stratified into mild, moderate, and high myopia.
  • High Pearson correlation coefficients between right and left eye refractive errors justified using right eye data for analysis.

Clinical Implications

Clinicians should consider that IOP in adolescents does not significantly differ by sex, suggesting similar monitoring strategies across genders. The associations between IOP and ocular parameters like axial length and corneal thickness highlight the importance of comprehensive ocular assessment in myopic children. Early identification of IOP variations may aid in understanding myopia progression and glaucoma risk in this population.

Conclusion

This study provides valuable data on IOP and its relationship with ocular characteristics in Chinese adolescents, emphasizing the need for further research on IOP’s role in myopia development. The findings support the integration of IOP measurement in routine ocular examinations for early detection and management of ocular conditions.

Related Resources & Content

  1. Anyang Childhood Eye Study Group 2024 -- Relationship Between Intraocular Pressure and Ocular Characteristics in Chinese Junior High Students

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