Clinical characteristics of acute pancreatitis in patients with inflammatory bowel disease: a nationwide survey in Japan - Report - MDSpire

Clinical characteristics of acute pancreatitis in patients with inflammatory bowel disease: a nationwide survey in Japan

  • By

  • Tetsuya Takikawa

  • Yoichi Kakuta

  • Kazuhiro Kikuta

  • Serina Haruyama

  • Ami Kawamoto

  • Shinichiro Shinzaki

  • Katsuyoshi Matsuoka

  • Hiroshi Nagai

  • Takanori Sano

  • Mikihiro Fujiya

  • Takuto Saiki

  • Masanao Nakamura

  • Atsushi Nishida

  • Sakiko Hiraoka

  • Takayuki Matsumoto

  • Katsuya Endo

  • Kazuyuki Narimatsu

  • Shojiro Yamamoto

  • Takashi Kagaya

  • Shin-ichiro Hagiwara

  • Noritaka Takatsu

  • Hiroshi Nakase

  • Kazuichi Okazaki

  • Yoki Furuta

  • Tetsu Kinjo

  • Soichiro Ishihara

  • Hirotake Sakuraba

  • Takashi Tashiro

  • Makoto Naganuma

  • Fukunori Kinjo

  • Tomohisa Takagi

  • Tadakazu Hisamatsu

  • Mitsuhiro Kawano

  • Atsushi Masamune

  • June 29, 2026

  • 0 min

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Characteristics of Acute Pancreatitis in Inflammatory Bowel Disease Patients

Overview

This nationwide study in Japan investigates the characteristics of acute pancreatitis (AP) in patients with inflammatory bowel disease (IBD), revealing a higher incidence of AP in IBD patients compared to the general population.

Background

Inflammatory bowel disease (IBD), including ulcerative colitis (UC) and Crohn's disease (CD), has seen a significant rise in prevalence, particularly in Japan. Acute pancreatitis (AP) is recognized as an extraintestinal manifestation of IBD, with a reported odds ratio of 3.11 for its occurrence in IBD patients.

Data Highlights

This study is a descriptive retrospective analysis of acute pancreatitis events in IBD patients across 28 institutions in Japan.

Key Findings

  • AP occurs more frequently in patients with IBD than in the general population.
  • Drug-induced AP is a common etiology in IBD patients.
  • Duodenal involvement is a significant risk factor for AP in patients with CD.
  • Type 2 autoimmune pancreatitis has been recognized as a cause of AP in patients with UC.

Clinical Implications

Clinicians should be aware of the increased risk of acute pancreatitis in IBD patients.

Conclusion

This study provides insights into the characteristics of acute pancreatitis in IBD patients.

Related Resources & Content

  1. Author(s)/Org, Source, Year -- Title
  2. Author(s)/Org, Source, Year -- Title
  3. Author(s)/Org, Source, Year -- Title
  4. Author(s)/Org, Source, Year -- Title
  5. Acute Pancreatitis in Inflammatory Bowel Disease: Results from the European Pandora Study
  6. Acute Pancreatitis in Inflammatory Bowel Disease: Results from the European Pandora Study
  7. https://pure.eur.nl/ws/files/209066127/International_Association_of_Pancreatology_Revised_Guidelines_on_Acute_Pancreatitis_2025.pdf

Original Source(s)

Clinical characteristics of acute pancreatitis in patients with inflammatory bowel disease: a nationwide survey in Japan

  • by Tetsuya Takikawa, Yoichi Kakuta, Kazuhiro Kikuta, Serina Haruyama, Ami Kawamoto, Shinichiro Shinzaki, Katsuyoshi Matsuoka, Hiroshi Nagai, Takanori Sano, Mikihiro Fujiya, Takuto Saiki, Masanao Nakamura, Atsushi Nishida, Sakiko Hiraoka, Takayuki Matsumoto, Katsuya Endo, Kazuyuki Narimatsu, Shojiro Yamamoto, Takashi Kagaya, Shin-ichiro Hagiwara, Noritaka Takatsu, Hiroshi Nakase, Kazuichi Okazaki, Yoki Furuta, Tetsu Kinjo, Soichiro Ishihara, Hirotake Sakuraba, Takashi Tashiro, Makoto Naganuma, Fukunori Kinjo, Tomohisa Takagi, Tadakazu Hisamatsu, Mitsuhiro Kawano, Atsushi Masamune

  • June 29, 2026

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