Investigating Physical Activity Patterns and Contributing Factors in Pediatric Leukemia Patients Undergoing Chemotherapy: A Cross-Sectional Analysis - Report - MDSpire

Investigating Physical Activity Patterns and Contributing Factors in Pediatric Leukemia Patients Undergoing Chemotherapy: A Cross-Sectional Analysis

  • By

  • Yuchen Chu

  • Rui Zhang

  • Chen Sun

  • Wanhua Ren

  • Peiying Wang

  • Tianxin Liu

  • Yunfeng Li

  • April 23, 2026

  • 0 min

Share

Clinical Report: Investigating Physical Activity Patterns in Pediatric Leukemia Patients

Overview

This study examines the physical activity levels of pediatric leukemia patients undergoing chemotherapy and identifies key factors influencing these levels. Findings indicate that a majority of patients engage in low-intensity activities, with significant predictors including chemotherapy phase and maternal support.

Background

Physical activity is crucial for the recovery of children with leukemia, yet maintaining activity levels during chemotherapy poses challenges. Understanding the factors that influence physical activity can help healthcare providers develop effective interventions to support these patients. This study provides insights into the relationship between physical activity and various psychosocial and treatment-related factors.

Data Highlights

VariableValue
Mean Age9.47 ± 3.16 years
Male Patients57.6%
Induction Phase30.7%
Consolidation Phase48.3%
Maintenance Phase20.9%
Active Participants9.3%

Key Findings

  • 87.3% of participants engaged in low-intensity physical activities.
  • Only 9.3% of participants met the criteria for moderate-to-vigorous physical activity.
  • Significant predictors of physical activity included chemotherapy phase, symptom burden, maternal support, and exercise self-efficacy.
  • These factors collectively explained 47.7% of the variance in physical activity levels.
  • Engagement in physical activity is essential for improving quality of life in pediatric leukemia patients.

Clinical Implications

Healthcare providers should consider the chemotherapy phase and family support when designing physical activity interventions for pediatric leukemia patients. Tailored programs that encourage family involvement and set individualized goals may enhance physical activity levels and overall well-being.

Conclusion

The study highlights the low physical activity levels among pediatric leukemia patients during chemotherapy and underscores the importance of targeted interventions. Addressing the identified influencing factors can improve patient outcomes and quality of life.

References

  1. Author(s)/Org, Source, Year -- Title
  2. Author(s)/Org, Source, Year -- Title
  3. Author(s)/Org, Source, Year -- Title
  4. The ASCO Post — Update on Lifestyle, Exercise, and Nutrition Early After Diagnosis (LEANer) Trial in Patients With Breast Cancer Guest Editor
  5. UK Children’s Cancer and Leukaemia Group Physical Activity Guidelines
  6. International Pediatric Oncology Exercise Guidelines
  7. Children’s Oncology Group Supportive Care Guidelines
  8. The effect of physical activity on health-related outcomes in children and adolescents with cancer: a systematic review and meta-analysis - PMC
  9. Grading the evidence on the effects of exercise interventions in children and adolescents during and beyond cancer treatment: an umbrella review of systematic reviews with meta-analyses - PubMed
  10. Efficacy of physical exercise intervention on children with acute lymphoblastic leukemia during treatment and rehabilitation: a systematic review and meta-analysis - PubMed
  11. Get strong to fight childhood cancer - an exercise intervention for children and adolescents undergoing anti-cancer treatment (FORTEe): Rationale and design of a randomized controlled exercise trial | BMC Cancer | Full Text
  12. Network Activeoncokids – Centralized Physical Activity Counseling for Children, adolescents, and Young Adults Across German-Speaking Countries Throughout All Oncological Treatment Phases - PMC

Original Source(s)

Related Content