Best practices and challenges in executing large scale pilots for eHealth deployment and managing innovation: the GATEKEEPER experience - Report - MDSpire

Best practices and challenges in executing large scale pilots for eHealth deployment and managing innovation: the GATEKEEPER experience

  • By

  • Davide Piaggio

  • Jordi de Batlle

  • Alba M. Gallego Montejo

  • Gloria Cea Sánchez

  • Pedro Checa Rifá

  • Alessia Maccaro

  • Rosana Angles Barbastro

  • Maria Teresa Hurtado

  • Jon Eneko Idoyaga Uribarrena

  • Irati Erreguerena Redondo

  • Maria Krini

  • Maria Matsangidou

  • Ioanna Drympeta

  • Konstantinos Votis

  • Alessio Antonini

  • Przemyslaw Kardas

  • Pawel Lewek

  • Julia Schellong

  • Francesco Giuliani

  • Franco Mercalli

  • Giuseppe Fico

  • Leandro Pecchia

  • the GATEKEEPER Consortium

  • May 29, 2026

  • 0 min

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Clinical Report: Effective Strategies and Obstacles in Implementing eHealth Pilots

Overview

The GATEKEEPER project provides a management framework for large-scale eHealth pilots, emphasizing best practices in usability, user-centered design, and recruitment strategies. This framework aims to enhance coordination and performance monitoring across diverse healthcare settings.

Background

The integration of digital health solutions is crucial for improving healthcare delivery and outcomes, particularly as healthcare systems increasingly rely on technology. However, the transition from small-scale pilots to large-scale implementations presents significant challenges, including ethical, legal, and technical considerations. Addressing these challenges is essential for the successful deployment of eHealth initiatives.

Data Highlights

Operational DomainBest Practices Ranked
EngagementUsability Testing
InterventionUser-Centered Digital Tool Design
RecruitmentActive Recruitment Strategies

Key Findings

  • The GATEKEEPER project developed a management framework over four years through mixed-methods research.
  • A panel of 23 experts ranked 45 best practices across six operational domains.
  • Usability testing and user-centered design were identified as top priorities for pilot sites.
  • The framework includes key performance indicators and a Business Intelligence dashboard for real-time monitoring.
  • Structured operational governance is critical for executing complex eHealth pilots.

Clinical Implications

Healthcare professionals should prioritize usability and user-centered design in digital health tools to enhance patient engagement. Additionally, implementing structured governance frameworks can facilitate the successful deployment of large-scale eHealth initiatives.

Conclusion

The GATEKEEPER project offers valuable insights into the effective implementation of large-scale eHealth pilots, highlighting the importance of best practices and structured governance in achieving sustainable digital health integration.

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