A volume-controlled, anatomy-driven autoplanning strategy for whole-pelvic volumetric modulated arc therapy - Report - MDSpire

A volume-controlled, anatomy-driven autoplanning strategy for whole-pelvic volumetric modulated arc therapy

  • By

  • Chih-Yuan Lin

  • An-Cheng Shiau

  • Ti-Hao Wang

  • Shih-Ming Hsu

  • May 7, 2026

  • 0 min

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Clinical Report: Anatomy-Based Automated Planning for Whole-Pelvic VMAT

Overview

The Volume-Controlled Autoplan (VCAP) demonstrates comparable PTV coverage and improved organ-at-risk (OAR) sparing in whole pelvic radiotherapy (WPRT) compared to traditional planning methods. VCAP significantly reduces planning time, enhancing efficiency while maintaining treatment quality.

Background

Whole pelvic radiotherapy (WPRT) is essential for managing pelvic malignancies but poses risks of toxicity to surrounding organs. Manual planning is labor-intensive and varies between planners, which can affect treatment consistency. Automated planning approaches like VCAP aim to improve efficiency and reduce variability while ensuring effective dose distribution.

Data Highlights

Dosimetric EndpointVCAPCPAPRP
PTV Coverage (V95)≥95%≥95%≥95%≥95%
Rectal Dose (V30)−24.6%Baseline−12%−13%
Bowel Bag Dose (V30)−20.5%BaselineN/AN/A
Mean Planning Time21 min120 minN/AN/A

Key Findings

  • VCAP achieved PTV coverage (V95) consistently above 95%.
  • Rectal doses were reduced by an average of 24.6% compared to clinical planning (CP).
  • Bowel bag exposure was decreased by more than 20.5% relative to CP.
  • Planning time was significantly reduced from approximately 120 minutes with CP to 21 minutes with VCAP.
  • VCAP maintained consistent plan quality across the patient cohort.

Clinical Implications

The VCAP approach enhances OAR sparing while ensuring robust PTV coverage, potentially leading to better patient outcomes. Its efficiency in planning time may allow for increased patient throughput in clinical settings.

Conclusion

VCAP represents a significant advancement in automated VMAT planning for WPRT, balancing efficiency and quality in treatment delivery. Further validation is needed to confirm its applicability in broader clinical contexts.

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