Detecting simulated skew deviation using a smartphone eye-tracking application (EyePhone): a feasibility study - Report - MDSpire

Evaluating Simulated Skew Deviation with a Smartphone Eye-Tracking Tool (EyePhone): A Feasibility Assessment

  • By

  • Rajvi Babaria

  • Pouya Barahim Bastani

  • Hector Rieiro

  • Shervin Badihian

  • Jorge Otero-Millan

  • Ali Saber Tehrani

  • July 21, 2026

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Clinical Report: Evaluating Simulated Skew Deviation with a Smartphone Eye-Tracking Tool

Overview

This study assesses the feasibility of using a smartphone application, EyePhone, to detect skew deviations, which are critical for diagnosing vestibular strokes. The findings indicate a strong correlation between EyePhone measurements and simulated skew deviations.

Background

Acute dizziness is a common presentation in emergency departments, with a significant proportion attributed to cerebrovascular accidents. Accurate diagnosis is crucial, as misdiagnosis can lead to severe outcomes, including increased mortality. The HINTS eye exam, particularly the test of skew, is essential for differentiating between central and peripheral causes of dizziness, yet its implementation is limited by the availability of trained personnel.

Data Highlights

The study demonstrated a Spearman correlation of 0.93 (CI: 0.90–0.95) between EyePhone measurements and designed skew deviations, with an area under the receiver operator curve of 0.90 for detecting clinically significant skew deviations (≥5 diopters).

Key Findings

  • Skew deviations of >5 diopters are highly specific for stroke.
  • The EyePhone application can potentially detect skew deviations in a controlled setting.
  • Correlation between EyePhone measurements and simulated skew deviations was strong (Spearman correlation of 0.93).
  • The area under the receiver operator curve for detecting skew deviations was 0.90.
  • Current methods for detecting skew deviations are limited by the availability of trained experts.

Clinical Implications

Further validation in clinical settings is necessary to confirm the effectiveness of the EyePhone application for assessing skew deviation.

Conclusion

The findings indicate that EyePhone measurements correlate strongly with clinically significant skew deviations.

Related Resources & Content

  1. SAEM, GRACE-3 Dizziness - Emergency Medicine Clinical Practice Guideline, 2023 -- https://www.saem.org/publications/grace/grace-3
  2. PMC, Head impulse, nystagmus, and test of skew examination for diagnosing central causes of acute vestibular syndrome, 2023 -- https://pmc.ncbi.nlm.nih.gov/articles/PMC10620998/?utm_source=openai
  3. PMC, Acute vestibular syndrome: is skew deviation a central sign?, 2023 -- https://pmc.ncbi.nlm.nih.gov/articles/PMC8857098/?utm_source=openai
  4. Frontiers in Digital Health — Enhancing access and clinical triage in primary eye care through digital vision testing: validation of the SightConnect mobile application
  5. Frontiers in Neurology — Validation of a portable video head impulse test using an iPod touch and an oral stabilization three-dimensional (3D) - printed mount: a method-comparison study
  6. Presbyopia Physician — A Wearable, Binocular, Widefield, Portable Visual Simulator to Facilitate Presbyopia-correcting IOL Selection
  7. npj Digital Medicine — A smartphone-based blink training application for alleviating dry eye signs and symptoms
  8. GRACE-3 Dizziness - Emergency Medicine Clinical Practice Guideline | SAEM
  9. Head impulse, nystagmus, and test of skew examination for diagnosing central causes of acute vestibular syndrome - PMC
  10. Acute vestibular syndrome: is skew deviation a central sign? - PMC

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