HFpEF risk assessment using H2FPEF score in community-dwelling young Hispanic adults - Report - MDSpire

HFpEF risk assessment using H2FPEF score in community-dwelling young Hispanic adults

  • By

  • Andrew Kim

  • Fadi I. Musfee

  • Soumya Patnaik

  • Miryoung Lee

  • Emma Molina

  • David D. McPherson

  • Joseph B. McCormick

  • Susan P. Fisher-Hoch

  • Susan T. Laing

  • May 29, 2026

  • 0 min

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Evaluating HFpEF Risk in Young Hispanic Adults Using the H2FPEF Score

Overview

This study highlights the prevalence of intermediate-high H2FPEF scores in a community-dwelling Hispanic cohort, particularly among young adults. It underscores the importance of using the H2FPEF score as a tool for early identification of HFpEF risk in asymptomatic populations.

Background

Heart failure with preserved ejection fraction (HFpEF) is a growing concern due to its association with high morbidity and mortality rates. The H2FPEF score is a validated tool that can help identify individuals at risk for HFpEF, especially in populations with high cardiometabolic risk, such as Hispanics. Understanding these risks is crucial for implementing preventive measures in vulnerable communities.

Data Highlights

Age GroupIntermediate-High Risk (% of cohort)
<60 years33%
Overall43%

Key Findings

  • 43% of the Hispanic cohort had intermediate-high H2FPEF scores.
  • 33% of participants under 60 years had intermediate-high H2FPEF scores.
  • Age, metabolic syndrome, higher hemoglobin A1c, and sedentary lifestyle were significantly associated with increased H2FPEF scores in young Hispanics.
  • The H2FPEF score can be a useful tool for identifying HFpEF risk in asymptomatic populations.
  • Hispanics have a high prevalence of cardiometabolic risk factors, increasing their risk for HFpEF.

Clinical Implications

Healthcare providers should consider using the H2FPEF score in community settings to identify young Hispanic adults at risk for HFpEF. Early identification and management of cardiometabolic risk factors may help prevent the progression of heart failure symptoms in this population.

Conclusion

The findings emphasize the need for proactive screening for HFpEF risk in young Hispanic adults, utilizing the H2FPEF score as a practical tool for early intervention.

Related Resources & Content

  1. Clinical Research in Cardiology, 2024 -- Diagnosis, Risk Evaluation, and Management of Heart Failure with Preserved Ejection Fraction
  2. Frontiers in Cardiovascular Medicine, 2026 -- E/e' Ratio Combined with Left Ventricular Mass Index Predicts HFpEF Rehospitalization Risk in Stage 3-4 Chronic Kidney Disease Patients
  3. Clinical Research in Cardiology, 2023 -- Prognostic Factors and Clinical Features in Patients with Hypertrophic Cardiomyopathy and Heart Failure with Preserved Ejection Fraction
  4. JACC, 2023 -- 2023 ACC Expert Consensus Decision Pathway on Management of Heart Failure With Preserved Ejection Fraction
  5. Clinical Research in Cardiology — The Impact of Comorbid Conditions on Functional Limitations is Greater in Heart Failure with Preserved Ejection Fraction Compared to Reduced Ejection Fraction
  6. Empagliflozin in Heart Failure with a Preserved Ejection Fraction - PubMed
  7. 2025 Heart Disease and Stroke Statistics: A Report of US and Global Data From the American Heart Association
  8. 2023 ACC Expert Consensus Decision Pathway on Management of Heart Failure With Preserved Ejection Fraction: A Report of the American College of Cardiology Solution Set Oversight Committee | JACC

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