Reply to: Organ donation after ECPR: ethical challenges and clinical implications - Report - MDSpire
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Response to: Ethical Considerations and Clinical Consequences of Organ Donation Post-ECPR

  • By

  • Sasa Rajsic

  • Eduard Argudo

  • Sylvia Maria Belda Hofheinz

  • María Martínez Martínez

  • Ana Delgado

  • Marta Velia Antonini

  • Jonah Rubin

  • Robert Breitkopf

  • September 25, 2026

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Response to: Ethical Considerations and Clinical Consequences of Organ Donation Post-ECPR

Overview

This correspondence addresses ethical challenges and clinical implications of organ donation after extracorporeal cardiopulmonary resuscitation (ECPR) as discussed by Moya Sánchez et al.

Background

Organ donation after ECPR presents unique ethical considerations, particularly regarding the intersection of resuscitation efforts and organ procurement, as highlighted by Moya Sánchez et al.

Data Highlights

No numerical data presented in the source material.

Key Findings

  • Structural risks in organ donation require careful contextualization to preserve patient-centered decision-making, as noted by Moya Sánchez et al.
  • The dead donor rule (DDR) mandates that death must be established before organ recovery, but ante-mortem interventions can be ethically justified, according to Moya Sánchez et al.
  • Spanish practices exemplify the separation of clinical decisions from donation considerations, ensuring independent evaluations, as reported by Moya Sánchez et al.
  • Communication with families regarding treatment limitations must precede discussions about organ donation, as emphasized by Moya Sánchez et al.
  • Proposed safeguards aim to maintain clinical independence while respecting patient wishes regarding organ donation, as outlined by Moya Sánchez et al.

Clinical Implications

Clinicians must navigate the complexities of organ donation after ECPR with a focus on ethical guidelines and patient autonomy, as discussed by Moya Sánchez et al.

Conclusion

The correspondence highlights the need for a structured approach to organ donation after ECPR, emphasizing ethical considerations as discussed by Moya Sánchez et al.

Related Resources & Content

  1. Moya Sánchez et al., Critical Care, 2026 -- Ethical Considerations and Clinical Consequences of Organ Donation Following ECPR
  2. Rajsic et al., Intensive Care Medicine, 2021 -- Organ Donation Following Controlled Cardiocirculatory Death: Enhancing Confidence Through Transparency
  3. Journal of Cardiac Failure, 2026 -- Increased Federal Oversight of Donation After Circulatory Death Heart Transplant: Time for a Pause?
  4. Intensive Care Medicine, 2021 -- Enhancing Controlled Organ Donation Following Circulatory Death: The Need for Greater Consideration of Cultural, Religious, and Legal Perspectives
  5. 2025 American Heart Association Guidelines for Cardiopulmonary Resuscitation and Emergency Cardiovascular Care
  6. Update on Normothermic Regional Perfusion—A Message to the OPTN Community | HRSA
  7. Normothermic regional perfusion in controlled donation after circulatory death liver transplantation: an updated systematic review and meta-analysis versus non-NRP and brain-death donors
  8. Part 3: Ethics: 2025 American Heart Association Guidelines for Cardiopulmonary Resuscitation and Emergency Cardiovascular Care
  9. Update on Normothermic Regional Perfusion—A Message to the OPTN Community | HRSA
  10. Frontiers Publishing Partnerships | Normothermic regional perfusion in controlled donation after circulatory death liver transplantation: an updated systematic review and meta-analysis versus non-NRP and brain-death donors

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