Clinical Report: Impact of Initial Hyperglycemia in Acute Ischemic Stroke
Overview
This study investigates the relationship between admission hyperglycemia and discharge outcomes in acute ischemic stroke patients. It finds that admission hyperglycemia significantly increases the odds of unfavorable discharge outcomes.
Background
Hyperglycemia is prevalent in acute ischemic stroke patients and is linked to poorer outcomes. Understanding its impact on stroke recovery is crucial, especially in regions with high diabetes prevalence. This study aims to clarify the role of hyperglycemia in stroke management and outcomes.
Data Highlights
Parameter
Value
Admission Hyperglycemia Prevalence
51.7%
Adjusted Odds Ratio for Unfavorable mRS
3.43 (95% CI 1.33–8.87, p = 0.011)
Pooled OR across NIHSS strata
3.47 (p<0.001)
Inappropriate Management in Hyperglycemic Patients
85.8%
Occult Diabetes Identified
18.4%
Key Findings
Admission hyperglycemia was present in 51.7% of patients.
It was associated with a tripled adjusted odds of unfavorable discharge outcomes (mRS 3–6).
Inappropriate glycemic management occurred in 85.8% of hyperglycemic patients.
Routine HbA1c testing revealed occult diabetes in 18.4% of patients.
No severe hypoglycemia was reported during the study.
Clinical Implications
The findings indicate a significant association between admission hyperglycemia and unfavorable discharge outcomes.
Baptist Health Brain & Spine Care Stroke Programs at nine Baptist Health hospitals have earned recognition from the American Heart Association and American Stroke Association.