Prone positioning in ARDS - Report - MDSpire

Utilization of Prone Positioning for Patients with ARDS

  • By

  • Stephan Ehrmann

  • Jie Li

  • Ling Liu

  • Claude Guérin

  • July 20, 2026

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Clinical Report: Utilization of Prone Positioning for Patients with ARDS

Overview

Prone positioning (PP) is an intervention in managing ARDS, showing benefits in intubated patients. Its application has expanded to non-intubated patients during the COVID-19 pandemic.

Background

Prone positioning has transitioned from a rescue maneuver to a component of ARDS management, supported by evidence. It enhances oxygenation and reduces ventilator-induced lung injury by improving lung mechanics and gas exchange. The uptake of PP varies across healthcare settings.

Data Highlights

No numerical data or trial data provided in the source material.

Key Findings

  • PP improves oxygenation in intubated patients with moderate-to-severe ARDS.
  • The PROSEVA trial demonstrated a reduction in 28-day mortality with early and prolonged PP.
  • Awake prone positioning (APP) has shown effects in non-intubated patients during the COVID-19 pandemic.
  • Implementation of PP varies despite guideline recommendations.
  • Physiological benefits of PP include improved ventilation-perfusion matching.

Clinical Implications

Healthcare professionals should consider the integration of prone positioning into management protocols for ARDS patients.

Conclusion

Prone positioning is an intervention in ARDS management, with evidence supporting its efficacy in intubated patients.

Related Resources & Content

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  5. An Update on Management of Adult Patients with Acute Respiratory Distress Syndrome: An Official American Thoracic Society Clinical Practice Guideline - PMC
  6. Prone Positioning in Severe Acute Respiratory Distress Syndrome
  7. Awake Prone Positioning in Adults With COVID-19
  8. An Update on Management of Adult Patients with Acute Respiratory Distress Syndrome: An Official American Thoracic Society Clinical Practice Guideline - PMC

Original Source(s)

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