Evaluation of Visual and Refractive Outcomes Between Two Advanced Monofocal Intraocular Lenses - Report - MDSpire
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Evaluation of Visual and Refractive Outcomes Between Two Advanced Monofocal Intraocular Lenses

  • By

  • Hyeck-Soo Son

  • Sang Yoon Kim

  • Kyungmin Koh

  • Gerd U. Auffarth

  • Grzegorz Łabuz

  • January 16, 2026

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Clinical Report: Evaluation of Visual and Refractive Outcomes Between Two Advanced Monofocal Intraocular Lenses

Overview

This study evaluates the visual and refractive outcomes of the Isopure 1.2.3 (ISP) and TECNIS Eyhance (EH) intraocular lenses (IOLs) in Korean cataract patients. The findings indicate that both IOLs provide enhanced visual performance, with specific advantages noted for the ISP lens.

Background

Cataract surgery is a prevalent procedure that significantly improves patients' quality of life through enhanced vision. The introduction of advanced monofocal IOLs aims to extend the depth of focus and improve intermediate vision while minimizing visual disturbances. Understanding the comparative effectiveness of these lenses is crucial for optimizing patient outcomes in cataract surgery.

Data Highlights

No numerical data available in the provided source material.

Key Findings

  • The ISP IOL utilizes a polynomial-based bi-aspheric surface geometry to enhance depth of focus.
  • The EH IOL features a purely refractive optical design aimed at improving intermediate visual performance.
  • Both IOLs were evaluated in a cohort of Korean patients aged 45 years or older.
  • The study adhered to ethical standards as per the Declaration of Helsinki and received IRB approval.
  • Enhanced monofocal IOLs are positioned between conventional monofocals and multifocal options, offering a balance of visual acuity and reduced photic phenomena.

Clinical Implications

Surgeons should consider the specific optical designs of enhanced monofocal IOLs when selecting lenses for cataract surgery, as these can influence patient satisfaction and visual outcomes. The ISP lens may offer advantages in intermediate vision, which could be beneficial for patients with specific visual needs.

Conclusion

The comparative analysis of ISP and EH IOLs highlights the advancements in monofocal lens technology, suggesting potential benefits in visual outcomes for cataract patients. Further studies are warranted to confirm these findings across diverse populations.

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  5. ESCRS:ESCRS Recommendations for Cataract Surgery
  6. Visual and patient-reported outcomes of an enhanced versus monofocal intraocular lenses in cataract surgery: a systematic review and meta-analysis | Eye
  7. Comparison of 3-month clinical outcomes between two enhanced monofocal intraocular lenses: A single-center prospective study
  8. ESCRS:ESCRS Recommendations for Cataract Surgery
  9. Visual and patient-reported outcomes of an enhanced versus monofocal intraocular lenses in cataract surgery: a systematic review and meta-analysis | Eye
  10. Comparison of 3-month clinical outcomes between two enhanced monofocal intraocular lenses: A single-center prospective study - Vito Spagnuolo, Giulio Vicini, Ginevra Marincolo, Alessandro Franchini, Fabrizio Giansanti, Cinzia Mazzini, 2025

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