Survey on the current status of photoaging in young Asian women and intervention effects of non-ablative bipolar radiofrequency combined with ablative fractional CO₂ laser: a retrospective study - Report - MDSpire

Survey on the current status of photoaging in young Asian women and intervention effects of non-ablative bipolar radiofrequency combined with ablative fractional CO₂ laser: a retrospective study

  • By

  • Xie Qiu

  • Wei Zhang

  • Xiaofeng Duan

  • May 1, 2026

  • 0 min

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Clinical Report: Assessment of Photoaging in Young Asian Women

Overview

This study evaluates the extent of photoaging in young Asian women and the efficacy of combined non-ablative bipolar radiofrequency and ablative fractional CO₂ laser treatments. Results indicate that the combined treatment significantly improves photoaging symptoms compared to RF alone, with no increase in adverse effects.

Background

Photoaging, primarily caused by UV radiation, significantly affects the skin's appearance and can lead to psychological distress. Young women, particularly those with Fitzpatrick skin types I–II, are at risk for premature photoaging due to inadequate sun protection and lifestyle factors. Understanding effective treatment modalities is crucial for improving skin health and aesthetics in this demographic.

Data Highlights

CohortEffective RateGPS ScoreAdverse Effects
RF-alone (n=80)78.75%2.24 ± 0.564.10%
Combined (n=122)95.08%1.58 ± 0.503.75%

Key Findings

  • 71.29% of patients were classified as Grade I and 28.71% as Grade II in the Glogau classification.
  • Combined treatment showed a significantly higher effective rate (95.08%) compared to RF alone (78.75%).
  • Post-treatment symptom scores for pore size, hyperpigmentation, skin texture, and skin color were significantly lower in the combined cohort.
  • Global photoaging score (GPS) decreased significantly in the combined cohort (mean difference: −0.66).
  • No significant difference in adverse reaction rates between the two cohorts was observed.

Clinical Implications

The findings suggest that combining non-ablative bipolar radiofrequency with ablative fractional CO₂ laser treatments is an effective strategy for managing early photoaging in young Asian women. Clinicians should consider this combined approach to enhance treatment outcomes while minimizing adverse effects.

Conclusion

The study highlights the effectiveness of combined non-ablative and ablative treatments in addressing photoaging in young Asian women, offering a safe and efficient therapeutic option. Further research may solidify these findings and optimize treatment protocols.

References

  1. Conexiant, Dual-Frequency Radiofrequency for Facial Laxity?, 2026 -- Dual-Frequency Radiofrequency for Facial Laxity?
  2. Ophthalmology Management, Relieving severe rosacea with IPL, 2018 -- Relieving severe rosacea with IPL
  3. Optometric Management, Recognizing and Treating Ocular Rosacea in Darker Skin Tones, 2026 -- Recognizing and Treating Ocular Rosacea in Darker Skin Tones
  4. Scientific Reports, Comparative efficacy of topical interventions for facial photoaging: a network meta-analysis, 2025 -- Comparative efficacy of topical interventions for facial photoaging
  5. Frontiers, Survey on the Current Status of Photoaging in Young Asian Women and Intervention Effects of Non-ablative Bipolar Radiofrequency Combined with Ablative Fractional CO₂ Laser: A Retrospective Study, 2026 -- Survey on the Current Status of Photoaging
  6. Optometric Management — Recognizing and Treating Ocular Rosacea in Darker Skin Tones
  7. Comparative efficacy of topical interventions for facial photoaging: a network meta-analysis | Scientific Reports
  8. Frontiers | Survey on the Current Status of Photoaging in Young Asian Women and Intervention Effects of Non-ablative Bipolar Radiofrequency Combined with Ablative Fractional CO₂ Laser: A Retrospective Study
  9. Potential Risks with Certain Uses of Radiofrequency (RF) Microneedling – FDA Safety Communication | FDA

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