Clinical Report: Ocular Biometric Features and Interocular Variability in Pediatric High Myopia
Overview
This study investigates the ocular biometric characteristics of pediatric high myopia, revealing significant correlations between age, axial length (AL), and axial length/corneal radius (AL/CR) ratio. The findings underscore the need for enhanced monitoring and intervention strategies for children with high myopia.
Background
The rising prevalence of myopia, particularly high myopia in children, poses significant public health challenges. Early-onset high myopia increases the risk of severe ocular complications later in life, necessitating a robust monitoring system for structural indicators beyond traditional refractive measurements. Understanding the biometric characteristics of high myopia is crucial for developing effective prevention and management strategies.
Data Highlights
Parameter
Value
Average SE
−8.87 ± 2.58D
Average AL
26.41 ± 1.33 mm
Average AL/CR
3.38 ± 0.19
Correlation of Age with AL
r = 0.485, P < 0.001
Correlation of Age with AL/CR
r = 0.505, P < 0.001
Annual AL Growth Rate
0.224 ± 0.264 mm/year
Key Findings
84 pediatric patients with high myopia were analyzed, with a mean SE of −8.87 ± 2.58D.
Significant positive correlations were found between age and both AL (r = 0.485) and AL/CR ratio (r = 0.505).
Age was an independent predictor of both AL and AL/CR, with a growth rate of 0.200 mm/year for AL.
27.7% of patients exhibited anisometropia with | ΔSE| ≥ 2.0D.
The annual growth rate of AL in the follow-up subset was approximately 0.224 ± 0.264 mm/year.
Clinical Implications
Clinicians should prioritize monitoring axial length and AL/CR ratios in children with high myopia to assess long-term risks. Enhanced individualized monitoring and intervention strategies are essential, particularly for patients with significant binocular asymmetry.
Conclusion
The study highlights the critical need for early risk assessment and tailored management strategies in pediatric high myopia, emphasizing the importance of ocular biometric indicators in clinical practice.