Development and evaluation of a preliminary risk assessment model for psychological distress among patients with brain tumors: a cross-sectional analysis - Report - MDSpire
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Development and evaluation of a preliminary risk assessment model for psychological distress among patients with brain tumors: a cross-sectional analysis

  • By

  • Ying Li

  • Yuyu Duan

  • Yangmei Su

  • Zhiman Zheng

  • Dongqi Zou

  • Zhihuan Zhou

  • January 22, 2026

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Clinical Report: Risk Assessment Model for Psychological Distress in Brain Tumors

Overview

This report evaluates a preliminary risk assessment model for psychological distress (PD) among patients with brain tumors, highlighting the significant prevalence of PD and its association with factors such as financial toxicity and self-efficacy. The findings underscore the necessity for early screening and targeted interventions to improve patient outcomes.

Background

Brain tumors pose a considerable health threat, with a notable incidence and mortality rate. Patients frequently experience psychological distress, which can severely impact their quality of life and treatment adherence. Understanding the risk factors associated with PD is essential for timely intervention and improved patient care.

Data Highlights

No specific numerical data or trial results were provided in the source material.

Key Findings

  • 44.5% to 76.0% of brain tumor patients experience clinically significant psychological distress.
  • Financial toxicity is strongly associated with increased psychological distress in brain tumor patients and caregivers.
  • Self-efficacy inversely correlates with psychological distress, where lower self-efficacy predicts higher distress levels.
  • Adaptive coping strategies, such as seeking social support, are linked to reduced psychological distress.
  • High anxiety and depression rates are reported among brain tumor patients during treatment, necessitating targeted psychosocial care.

Clinical Implications

Healthcare providers should prioritize early screening for psychological distress in brain tumor patients, considering factors such as financial toxicity and self-efficacy. Implementing targeted psychosocial interventions can help mitigate distress and enhance overall patient quality of life.

Conclusion

The development of a risk assessment model for psychological distress in brain tumor patients is crucial for improving patient care. Early identification and intervention can significantly impact patient outcomes and quality of life.

Related Resources & Content

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  5. NCCN Guidelines® Insights - Distress Management, Version 1.2026 | NCCN Continuing Education
  6. Understanding the Trajectory of Depressive Symptoms in Newly Diagnosed High-Grade Glioma Patients—A Meta-Analysis - PMC
  7. NCCN Guidelines® Insights - Distress Management, Version 1.2026 | NCCN Continuing Education
  8. Understanding the Trajectory of Depressive Symptoms in Newly Diagnosed High-Grade Glioma Patients—A Meta-Analysis - PMC
  9. https://www.brainlife.org/fulltext/2025/Renovanz_M250910_JNeurooncol.pdf

Original Source(s)

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