Influence of patients’ sex on radiomics-based predictions of lung artery thrombus - Report - MDSpire

Influence of patients’ sex on radiomics-based predictions of lung artery thrombus

  • By

  • Lea Ehrhardt

  • Georg Hille

  • Ehsan Amini

  • Alexey Surov

  • Jan Borggrefe

  • Patrique Fiedler

  • Sylvia Saalfeld

  • June 4, 2026

  • 0 min

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Clinical Report: Impact of Patient Gender on Radiomics Predictions for Lung Artery Thrombus

Overview

This study investigates the influence of patient gender on radiomics-based predictions of mortality and troponin levels in acute pulmonary embolism (APE). It highlights the need for further understanding of gender differences in clinical outcomes related to APE.

Background

Acute pulmonary embolism (APE) is a prevalent cardiovascular condition with significant mortality rates. The role of gender in clinical presentations and outcomes of APE remains inadequately explored, as women are often underrepresented in clinical studies. Understanding these differences is crucial for improving diagnostic and treatment strategies.

Data Highlights

No numerical data or trial results were provided in the source material.

Key Findings

  • The study utilized a dataset of 427 APE patients, including 200 patients (100 female and 100 male) for analysis.
  • Previous research has shown conflicting results regarding sex differences in mortality rates among APE patients.
  • Gender differences in clinical portrayal and outcomes have been documented but remain poorly understood.
  • The study aims to clarify the impact of sex on radiomics-based predictions of mortality and troponin levels.
  • Machine learning workflows were employed to analyze the medical imaging data.

Clinical Implications

The findings suggest that gender may play a role in the radiomics-based prediction of mortality in APE. Clinicians should consider gender differences when interpreting radiomics data and assessing patient outcomes.

Conclusion

This investigation into the impact of gender on radiomics predictions in APE highlights the necessity for further research to enhance understanding and improve patient management.

Related Resources & Content

  1. Evaluating the Prognostic Value of Radiomic Analysis of Pulmonary Artery Thrombus in Patients with Pulmonary Embolism, Springer, 2025 -- Evaluating the Prognostic Value of Radiomic Analysis of Pulmonary Artery Thrombus in Patients with Pulmonary Embolism
  2. Anthropometry, sex, and age at diagnosis affect pulmonary blood volume quantification from computed tomography pulmonary angiography in pulmonary hypertension assessment, Frontiers in Cardiovascular Medicine, 2026 -- Anthropometry, sex, and age at diagnosis affect pulmonary blood volume quantification from computed tomography pulmonary angiography in pulmonary hypertension assessment
  3. Gender Differences in Deep Learning Assessment of Ejection Fraction via Cardiac Magnetic Resonance Imaging, npj Digital Medicine, 2025 -- Gender Differences in Deep Learning Assessment of Ejection Fraction via Cardiac Magnetic Resonance Imaging
  4. 2026 Guideline for the Evaluation and Management of Acute Pulmonary Embolism in Adults, American Heart Association -- 2026 Guideline for the Evaluation and Management of Acute Pulmonary Embolism in Adults
  5. The ASCO Post — Comprehensive CT Scans May Help to Identify Atherosclerosis Among Patients With Lung Cancer
  6. 2026 Guideline for the Evaluation and Management of Acute Pulmonary Embolism in Adults - Professional Heart Daily | American Heart Association
  7. Ultrasound-Facilitated, Catheter-Directed Fibrinolysis for Acute Pulmonary Embolism | New England Journal of Medicine
  8. Disparities in Current Pulmonary Embolism Management and Outcomes: A Scientific Statement From the American Heart Association - PMC

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