Case Report: Erythema gyratum repens associated with adenomyosis and endometriosis: an immunological twist? - Report - MDSpire

Case Report: Erythema gyratum repens associated with adenomyosis and endometriosis: an immunological twist?

  • By

  • Emanuele Scala

  • Donatella Sordi

  • Arlind Kalaja

  • Francesca Passarelli

  • Lidia Francesconi

  • Filomena Russo

  • July 10, 2026

  • 0 min

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Clinical Report: Erythema Gyratum Repens Linked to Adenomyosis and Endometriosis

Overview

This case study presents a 37-year-old woman with erythema gyratum repens (EGR) associated with severe adenomyosis and endometriosis. Following a total hysterectomy, the patient's cutaneous symptoms resolved completely within two months.

Background

Erythema gyratum repens (EGR) is a rare dermatosis often linked to paraneoplastic syndromes, but it can also occur in non-paraneoplastic contexts. Understanding potential non-paraneoplastic triggers, such as chronic inflammatory gynecological diseases, is crucial for accurate diagnosis.

Data Highlights

No numerical or trial data available in the source material.

Key Findings

  • A 37-year-old woman presented with a 2-year history of pruritic concentric erythematous plaques.
  • Her clinical presentation was suggestive of EGR, typically associated with paraneoplastic conditions.
  • Laboratory tests revealed an elevated CA-125 level, prompting further gynecological assessment.
  • Severe adenomyosis and concomitant endometriosis were diagnosed, leading to a total hysterectomy.
  • The cutaneous eruption resolved completely within 2 months post-surgery without additional dermatologic treatment.
  • This case expands the understanding of non-paraneoplastic conditions associated with EGR.

Clinical Implications

Clinicians should consider both paraneoplastic and non-paraneoplastic causes when evaluating patients with EGR.

Conclusion

This case highlights the association of EGR with chronic gynecological conditions.

Related Resources & Content

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  5. Erythema Gyratum Repens - an overview | ScienceDirect Topics
  6. Overview | Endometriosis: diagnosis and management | Guidance | NICE
  7. Immunopathological insights into endometriosis: from research advances to future treatments | Seminars in Immunopathology | Springer Nature Link
  8. Erythema Gyratum Repens - an overview | ScienceDirect Topics
  9. Overview | Endometriosis: diagnosis and management | Guidance | NICE
  10. Immunopathological insights into endometriosis: from research advances to future treatments | Seminars in Immunopathology | Springer Nature Link

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