Tuina combined with other therapies for treating insomnia: a systematic review and network meta-analysis - Report - MDSpire

Tuina combined with other therapies for treating insomnia: a systematic review and network meta-analysis

  • By

  • Zihang Tong

  • Shun Fan

  • Yusheng Li

  • Qiaoling Chen

  • Huanan Li

  • Jingui Wang

  • May 28, 2026

  • 0 min

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Clinical Report: Integration of Tuina with Additional Treatments for Insomnia

Overview

This systematic review and network meta-analysis evaluated the effectiveness of various Tuina-based combination therapies for insomnia. The findings suggest that certain combinations, particularly Tuina with breath guiding and acupoint application, show significant improvements over oral medication.

Background

Insomnia is a prevalent condition that adversely affects physical and mental health, increasing the risk of various diseases. Current treatments primarily involve pharmacotherapy and cognitive-behavioral therapy, both of which have limitations. Tuina, a non-pharmacological intervention, may offer a viable alternative, especially when combined with other therapies.

Data Highlights

InterventionOutcomeSignificance
Tuina + breath guiding + acupoint applicationTotal effective rateP < 0.05
Tuina + musicTotal effective rateP < 0.05
Tuina + foot bathTotal effective rateP < 0.05
Tuina + acupuncturePSQI score improvementP < 0.05

Key Findings

  • Thirty-four RCTs with 2,663 subjects were included in the analysis.
  • Tuina-based combinations showed a statistically significant improvement in total effective rate compared to oral medication.
  • The top-ranked interventions were Tuina + breath guiding + acupoint application, Tuina + music, and Tuina + foot bath.
  • Tuina + acupoint application had the lowest rate of adverse events among the combinations studied.
  • Most evidence quality was assessed as low or very low, indicating a need for further research.

Clinical Implications

The findings suggest that Tuina-based combination therapies may provide a beneficial alternative to pharmacotherapy for insomnia management. However, the low quality of evidence highlights the necessity for further high-quality RCTs to confirm these results.

Conclusion

Tuina-based combination therapies demonstrate potential advantages over drug monotherapy for insomnia, warranting further investigation to validate these findings.

Related Resources & Content

  1. Frontiers in Neurology, 2026 -- Tuina combined with other therapies for treating insomnia: A systematic review and network meta-analysis
  2. Frontiers in Neurology — Comparative effectiveness of acupuncture and Tuina for cervical vertigo: a systematic review and network meta-analysis of randomized controlled trials
  3. conexiant — New Guidance on Chronic Insomnia Treatment
  4. npj Digital Medicine — Advancing Comprehensive Sleep Health: The Role of Multimodal AI in the Hang Hao Meng Agent
  5. Frontiers in Neurology — Adjunctive electroacupuncture to facilitate discontinuation of non-benzodiazepine hypnotics in chronic insomnia: a randomized controlled trial protocol
  6. New Guidance on Chronic Insomnia Treatment
  7. Advancing Comprehensive Sleep Health: The Role of Multimodal AI in the Hang Hao Meng Agent
  8. https://www.healthquality.va.gov/HEALTHQUALITY/guidelines/CD/insomnia/I-OSA-CPG_2025-Guideline_final_20250915.pdf
  9. Frontiers | Tuina combined with other therapies for treating insomnia:A systematic review and network meta-analysis
  10. Efficacy and safety of auriculotherapy for insomnia disorder: A randomized controlled trial - PubMed
  11. Massage positively influences daytime brain activity and reduces arousal state in poor sleepers: a randomized controlled trial | BMC Complementary Medicine and Therapies | Springer Nature Link

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