Radon balneotherapy in rheumatologic diseases: potential mechanisms and implications for cardiovascular autonomic control and inflammation - Report - MDSpire

Radon balneotherapy in rheumatologic diseases: potential mechanisms and implications for cardiovascular autonomic control and inflammation

  • By

  • Gabriel D. Rodrigues

  • Earric Lee

  • Benoit Dugué

  • Christian Hanshans

  • Maria Chiara Maccarone

  • Konstantinos Triantafyllias

  • Arnulf Hartl

  • Eugenijus Kaniusas

  • Sabrina Mörkl

  • Thomas E. Schmid

  • Goda-Camille Mickeviciute

  • Hannes Untner

  • Werner Klingler

  • Martin Offenbächer

  • June 24, 2026

  • 0 min

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Clinical Report: Exploring the Role of Radon Balneotherapy in Rheumatologic Conditions

Overview

This review synthesizes current evidence on radon balneotherapy's effects on rheumatologic conditions, focusing on its application in managing inflammation and autonomic regulation. It discusses the physiological mechanisms through which radon exposure may influence health in affected patients.

Background

Rheumatologic diseases are chronic conditions that damage joints and may increase systemic health risks, including cardiovascular issues. The exploration of complementary therapies like radon balneotherapy is important as they may provide additional management options for these complex diseases.

Data Highlights

No numerical data or trial results were provided in the source material.

Key Findings

  • Radon balneotherapy combines low-dose radon exposure with immersion in mineral-rich waters.
  • The therapy may modulate inflammation and enhance antioxidant activity.
  • Radon exposure is believed to activate cellular defense pathways.
  • There is historical use of radon therapy in conditions like rheumatoid arthritis and ankylosing spondylitis.
  • Current evidence on the efficacy and safety of radon balneotherapy is inconclusive.

Clinical Implications

Healthcare professionals should be aware of radon balneotherapy as a treatment option for patients with rheumatologic conditions.

Conclusion

Radon balneotherapy is a treatment approach for rheumatologic diseases. Further research is needed to clarify its role in clinical practice.

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  6. Frontiers in Immunology — Mechanistic study on the reduction of TNF-α and β-CTX levels in RA patients by moxibustion combined with western medication through regulation of the Wnt/β-catenin pathway
  7. EULAR Recommendations Management
  8. Health Effects from Exposure to Radon
  9. Efficacy and safety of balneotherapy in rheumatology: a systematic review and meta-analysis | BMJ Open
  10. The effectiveness of a 3-week spa therapy on the 6-month mobility and functional ability of patients with knee osteoarthritis: the ANGELLO randomized controlled trial | International Journal of Biometeorology | Springer Nature Link
  11. Radon Spa Therapy for the Treatment of Musculoskeletal Disorders: A Systematic Review and Meta-Analysis - PubMed
  12. Lower Heart Rate Variability is Associated with High Disease Activity, Functional Disability and Inflammation in Rheumatoid Arthritis: A Cross-Sectional Study - PubMed
  13. Enhancing detection of subclinical cardiac involvement in ankylosing spondylitis: the role of 3D systolic dyssynchrony index and autonomic dysfunction parameters | European Heart Journal | Oxford Academic
  14. Vagus nerve-mediated neuroimmune modulation for rheumatoid arthritis: a pivotal randomized controlled trial | Nature Medicine

Original Source(s)

Radon balneotherapy in rheumatologic diseases: potential mechanisms and implications for cardiovascular autonomic control and inflammation

  • by Gabriel D. Rodrigues, Earric Lee, Benoit Dugué, Christian Hanshans, Maria Chiara Maccarone, Konstantinos Triantafyllias, Arnulf Hartl, Eugenijus Kaniusas, Sabrina Mörkl, Thomas E. Schmid, Goda-Camille Mickeviciute, Hannes Untner, Werner Klingler, Martin Offenbächer

  • June 24, 2026

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