Dynamic contrast-enhanced liver MRI in children: image quality comparison between GRASP-VIBE and CAIPIRINHA-VIBE - Report - MDSpire

Dynamic contrast-enhanced liver MRI in children: image quality comparison between GRASP-VIBE and CAIPIRINHA-VIBE

  • By

  • Simon Veldhoen

  • Anne Pohrt

  • Matthias Stephan Anders

  • Corona Metz

  • May 21, 2026

  • 0 min

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Clinical Report: Comparative Analysis of Image Quality in Dynamic Contrast-Enhanced Liver MRI for Children

Overview

This study compares the image quality of GRASP-VIBE and CAIPIRINHA-VIBE techniques in pediatric dynamic contrast-enhanced liver MRI. The findings indicate that GRASP-VIBE may provide superior image quality in this population, addressing challenges related to breath-holding.

Background

MRI is essential for diagnosing and monitoring liver diseases in children, offering superior soft-tissue contrast without radiation exposure. Dynamic contrast-enhanced imaging is critical for accurate lesion detection and characterization, but achieving high-quality images in pediatric patients is challenging due to their limited breath-holding capabilities. This study evaluates new imaging techniques to improve diagnostic outcomes in this vulnerable population.

Data Highlights

No numerical data provided in the source material.

Key Findings

  • GRASP-VIBE allows continuous acquisition during free breathing, reducing motion artifacts.
  • CAIPIRINHA-VIBE relies on breath-holding, which can be difficult for young children.
  • The study included pediatric patients under 18 years who underwent liver MRI at a tertiary center.
  • Image quality was assessed across multiple dynamic contrast-enhanced phases.
  • GRASP-VIBE may enhance diagnostic capabilities in pediatric liver imaging.

Clinical Implications

The findings suggest that GRASP-VIBE could be a valuable alternative to CAIPIRINHA-VIBE for pediatric liver MRI, potentially reducing the need for sedation or anesthesia. Clinicians may consider adopting free-breathing techniques to improve image quality in young patients.

Conclusion

The study highlights the potential advantages of GRASP-VIBE over traditional breath-hold techniques in pediatric liver MRI. Further research may solidify its role in clinical practice.

Related Resources & Content

  1. Dynamic contrast-enhanced liver MRI in children: image quality comparison between GRASP-VIBE and CAIPIRINHA-VIBE, European Radiology, 2026 -- Title
  2. European Radiology — Improving Liver MRI with Gadoxetic Acid: A Combined Method Utilizing Deep Learning CAIPIRINHA-VIBE and Enhanced Fat Suppression Techniques
  3. European Radiology — Advancements in 4D FreeBreathing Method Enhance Pediatric Abdominal MRI Feasibility and Image Quality
  4. European Radiology — Assessment of Advanced Processing in Simultaneous Multi-Slice Acquisition for Free-Breathing Diffusion-Weighted Imaging in Liver Metastasis Patients
  5. European Radiology — Evaluating Image Quality and Diagnostic Precision of a Deep Learning Reconstruction Algorithm in Low-Dose Liver CT
  6. Best practices for pediatric liver MRI: guidelines from members of the Society for Pediatric Radiology Magnetic Resonance and Abdominal Imaging Committees
  7. https://mriquestions.com/uploads/3/4/5/7/34572113/acr-manual-on-contrast-media_2024.pdf
  8. Imaging of Pediatric Liver Tumors: A COG Diagnostic Imaging Committee/SPR Oncology Committee White Paper - PMC
  9. Hepatobiliary MR Imaging with Gadolinium Based Contrast Agents - PMC
  10. AHEP1531: Pediatric Hepatic Malignancy International Therapeutic Trial (PHITT) | University of Iowa Clinical Research and Trials
  11. 2017 PRETEXT: radiologic staging system for primary hepatic malignancies of childhood revised for the Paediatric Hepatic International Tumour Trial (PHITT) | CoLab
  12. Dynamic contrast-enhanced liver MRI in children: image quality comparison between GRASP-VIBE and CAIPIRINHA-VIBE | European Radiology | Springer Nature Link

Original Source(s)

Dynamic contrast-enhanced liver MRI in children: image quality comparison between GRASP-VIBE and CAIPIRINHA-VIBE

  • by Simon Veldhoen, Anne Pohrt, Matthias Stephan Anders, Corona Metz

  • May 21, 2026

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