Telerehabilitation robotics for upper limb rehabilitation after stroke (TRUST): a multi-site pragmatic trial protocol - Report - MDSpire

Telerehabilitation robotics for upper limb rehabilitation after stroke (TRUST): a multi-site pragmatic trial protocol

  • By

  • Ravi Shankar

  • Silvana Xinyi Choo

  • Zhenzhen Chen

  • Christopher Wee Keong Kuah

  • Tegan Kate Plunkett

  • Chwee Yin Ng

  • Sijie Lin

  • Kim Huat Goh

  • Emily Yee

  • Xiaojia Ge

  • Doris Zhang

  • Wei Binh Chong

  • Jaclyn Ai Mei Low

  • Megan Si En Lau

  • Xin Yi Lim

  • Saung Yupar Naing

  • Lian Ting Wong

  • Bernardo Noronha

  • Gabriel Aguirre-Ollinger

  • Asif Hussain

  • Poo Lee Ong

  • Karen Sui Geok Chua

  • May 21, 2026

  • 0 min

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Clinical Report: Robotic Telerehabilitation for Upper Limb Recovery Following Stroke

Overview

The TRUST trial aims to evaluate the feasibility and effectiveness of home-based robotic telerehabilitation for upper limb recovery in stroke patients. This innovative approach seeks to address the rehabilitation gap post-discharge, potentially transforming stroke care delivery.

Background

Stroke is a leading cause of long-term disability, with upper limb impairment affecting 39% of survivors at six months. The decline in therapy intensity after hospital discharge poses significant challenges to recovery. Home-based robotic therapy could provide an effective solution to enhance rehabilitation access and outcomes for stroke survivors.

Data Highlights

No numerical data available in the provided source material.

Key Findings

  • The TRUST trial will recruit 54 adults with moderate upper limb impairment post-stroke.
  • Participants will undergo four weeks of intensive home-based training with the H-Man robot.
  • Weekly telemonitoring will complement the robotic training and conventional occupational therapy sessions.
  • Primary outcome measures include compliance rates and secondary outcomes assess motor impairment, functional capacity, and quality of life.
  • Preliminary feasibility testing indicates acceptable device usability and caregiver support requirements.

Clinical Implications

The TRUST trial highlights the potential for integrating robotic telerehabilitation into standard post-stroke care, addressing the critical rehabilitation gap. Successful outcomes could lead to broader implementation of technology-enabled therapies in resource-limited settings.

Conclusion

The TRUST trial represents a significant step towards enhancing stroke rehabilitation through innovative home-based robotic therapy. Results will inform future strategies for integrating such interventions into routine care.

Related Resources & Content

  1. Frontiers in Neurology, 2026 -- Effects of blood flow restriction combined with robot-assisted training on upper limb motor function after stroke: a randomized controlled trial protocol
  2. npj Digital Medicine, 2025 -- Utilizing Immersive Virtual Reality for Rehabilitation of Hand and Finger Function: Findings from a Randomized Controlled Trial Involving 150 Patients with Traumatic Hand Injuries
  3. European Journal of Preventive Cardiology, 2023 -- A digitally supported shared decision-making approach for patients during cardiac rehabilitation: a randomized controlled trial
  4. npj Digital Medicine, 2026 -- Affordable AI-Powered Exergame for Stroke Rehabilitation and Upper-Limb Function Evaluation
  5. VA DoD CPG for Management of Stroke Rehabilitation, 2024 -- Stroke Rehabilitation Guidelines
  6. Efficacy of Robot-assisted Training on Upper Limb Motor Function After Stroke: A Systematic Review and Network Meta-analysis, 2024
  7. Telerehabilitation in post-stroke care: a systematic review and meta-analysis of randomized controlled trials, 2023
  8. VA DoD CPG for Management of Stroke Rehabilitation
  9. Efficacy of Robot-assisted Training on Upper Limb Motor Function After Stroke: A Systematic Review and Network Meta-analysis - ScienceDirect
  10. Telerehabilitation in post-stroke care: a systematic review and meta-analysis of randomized controlled trials - PubMed

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