Cognitive reappraisal as a component of process-based misophonia treatment: a mixed-methods pilot study of feasibility, acceptability and initial outcomes - Report - MDSpire

Cognitive reappraisal as a component of process-based misophonia treatment: a mixed-methods pilot study of feasibility, acceptability and initial outcomes

  • By

  • Marta Siepsiak

  • Andrzej Śliwerski

  • Anna Turek-Wojnarowicz

  • Weronika Araszkiewicz

  • Małgorzata Gambin

  • Mark Zachary Rosenthal

  • June 24, 2026

  • 0 min

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Clinical Report: Exploring Cognitive Reappraisal in Treatment for Misophonia

Overview

This pilot study evaluated the feasibility and acceptability of a cognitive reappraisal protocol tailored for misophonia. Preliminary results indicated a reduction in externalizing responses to misophonia triggers post-treatment.

Background

Misophonia is characterized by significant distress and functional impairment in response to specific sounds, affecting an estimated 2-4% of the population. Current treatment options are limited, with cognitive behavioral therapies showing potential but lacking specific evidence for misophonia.

Data Highlights

AssessmentResults
Externalizing ResponsesEstimate = -8.47, SE = 2.32, t(42.45) = -3.65, p < 0.001

Key Findings

  • No significant changes in three of the five symptom subscales between pre-treatment assessments.
  • Significant post-treatment reduction in externalizing responses to misophonia triggers.
  • Qualitative feedback indicated feelings of isolation and appreciation for the group format.
  • Participants expressed a need for more individualized support in treatment.

Clinical Implications

The findings suggest that cognitive reappraisal may be a beneficial component in treating misophonia. Tailoring interventions to individual patient needs and experiences is essential for enhancing treatment effectiveness.

Conclusion

Cognitive reappraisal warrants further controlled studies to validate these preliminary findings.

Related Resources & Content

  1. BMC Psychiatry (Springer) — Autonomic regulation during cognitive reappraisal in major depressive disorder: a study of fMRI correlates
  2. Journal of Medical Internet Research (JMIR) — A Self-Guided App-Based Mindfulness Intervention for Racially and Ethnically Minoritized Individuals Who Experience Discrimination-Related Mental Health Symptoms: Randomized Controlled Trial
  3. Frontiers in Psychiatry — Virtual reality based attentional bias modification training for patients with obsessive-compulsive disorder: a feasibility study
  4. BMC Psychiatry (Springer) — Evaluating the Effectiveness of Computer-Assisted Cognitive Remediation (CACR) for Schizophrenia: Results from a Randomized Controlled Trial
  5. Frontiers | Consensus Definition of Misophonia: A Delphi Study
  6. Cognitive behavioral therapy for misophonia: A randomized clinical trial - PMC
  7. Frontiers | Consensus Definition of Misophonia: A Delphi Study
  8. Cognitive behavioral therapy for misophonia: A randomized clinical trial - PMC

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