Case Report: Sellar collision tumor consisting of pituitary adenoma and craniopharyngioma, with literature review - Report - MDSpire

Case Report: Sellar collision tumor consisting of pituitary adenoma and craniopharyngioma, with literature review

  • By

  • Junhao Jin

  • Bin Gu

  • Guojian Wu

  • Jun Kong

  • Huilin Cheng

  • Xiaoying Wei

  • July 6, 2026

  • 0 min

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Clinical Report: A Rare Sellar Collision Tumor Comprising Pituitary Adenoma and Craniopharyngioma

Background

Collision tumors, particularly those involving the pituitary gland, are exceedingly rare and pose significant diagnostic challenges. The coexistence of pituitary adenoma and craniopharyngioma at the same site complicates both imaging and surgical management.

Data Highlights

No numerical data or trial data available in the source material.

Key Findings

  • The patient exhibited symptoms of fatigue, anorexia, and severe electrolyte disturbances.
  • Preoperative MRI showed a homogeneous lesion in the sellar region, indistinguishable from a macroadenoma.
  • Intraoperative findings revealed severe adhesion and significant hemorrhage (800 mL) during resection.
  • Pathology confirmed the presence of a Null-cell adenoma and Adamantinomatous craniopharyngioma.
  • Postoperative management included hormone replacement therapy, leading to stable recovery.

Clinical Implications

This case highlights the complexities involved in the management of collision tumors.

Conclusion

The occurrence of collision tumors in the sellar region presents unique challenges in diagnosis and management.

Related Resources & Content

  1. Assessment of Hormonal Replacement Needs Before and After Surgery for Non-Adenomatous Lesions in the Sellar and Parasellar Regions: The Role of the Sellar Encroachment Score, 2020
  2. Case Series and Systematic Review of Metastatic Meningioma, 2023
  3. Case Report: Giant communicating solitary fibrous tumor of the temporal skull base and infratemporal fossa, 2026
  4. Clinical and Molecular Characteristics of Sellar Neurocytoma: A Retrospective Analysis, 2025
  5. Pituitary Macroadenoma and Adamantinomatous Craniopharyngioma: A Rare Case Report of Sellar Collision Tumors, 2025
  6. Pituitary incidentaloma: a Pituitary Society international consensus guideline statement, 2025
  7. Evolution of surgical management and functional outcomes of craniopharyngiomas: a systematic review and meta-analysis, 2026
  8. Pituitary Macroadenoma and Adamantinomatous Craniopharyngioma: A Rare Case Report of Sellar Collision Tumors - PubMed
  9. Pituitary incidentaloma: a Pituitary Society international consensus guideline statement | Nature Reviews Endocrinology
  10. Evolution of surgical management and functional outcomes of craniopharyngiomas: a systematic review and meta-analysis

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