Type IV laryngo-tracheo-esophageal cleft with CPAM in a preterm twin- a case report - Report - MDSpire

Type IV laryngo-tracheo-esophageal cleft with CPAM in a preterm twin- a case report

  • By

  • Chee Mun Chan

  • Palaniappan Janaki Abirami

  • Agnihotri Biswas

  • Khadijah Binti Abdul Kader

  • July 15, 2026

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Clinical Report: Type IV Laryngo-Tracheo-Esophageal Cleft in Preterm Twin

Background

Laryngo-tracheo-esophageal cleft (LTEC) is a rare congenital anomaly resulting from incomplete separation of the foregut, with Type IV being the most severe form. These defects are associated with significant clinical challenges, necessitating a multidisciplinary approach to care.

Data Highlights

No numerical or trial data were provided in the source material.

Key Findings

  • Type IV LTEC is characterized by a common tracheoesophageal lumen and absent posterior tracheal wall.
  • Diagnosis of LTEC often requires direct laryngoscopy and bronchoscopy for accurate assessment.
  • Antenatal ultrasound may detect associated anomalies like CPAM but has limitations in visualizing posterior laryngeal structures.
  • Management of Type IV LTEC is complicated by significant pulmonary and gastrointestinal anomalies, as well as low birth weight.

Clinical Implications

Clinicians should be aware of the complexities involved in diagnosing and managing Type IV LTEC, particularly in the context of associated anomalies like CPAM.

Conclusion

This case highlights the diagnostic challenges associated with Type IV LTEC, particularly when significant associated anomalies are present.

Related Resources & Content

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  2. Pediatric Cardiology, 2025 -- Fetal Hypoplastic Left Heart Syndrome and Turner Syndrome Presenting with Nutmeg Lung Pattern on MRI
  3. Frontiers in Pediatrics, 2026 -- Case Report: Imaging findings of neonatal horseshoe lung with multiple system malformations
  4. Laryngeal Clefts - StatPearls - NCBI Bookshelf, 2023
  5. Congenital Pulmonary Airway Malformation | Treatment & Management | Point of Care - StatPearls, 2023
  6. Pediatric Cardiology — Inverted Cardiac Position with Aortopulmonary Window and Significant Airway Malacia: A Case of Prenatal Diagnosis and Literature Review
  7. Laryngeal Clefts - StatPearls - NCBI Bookshelf
  8. Congenital Pulmonary Airway Malformation | Treatment & Management | Point of Care - StatPearls
  9. Neonatal Life Support: 2025 International Liaison Committee on Resuscitation Consensus on Science With Treatment Recommendations | Pediatrics | American Academy of Pediatrics

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