Association between blood pressure levels and risk of stroke in patients with atrial fibrillation: results from a prospective registry in Xinjiang, China - Report - MDSpire

Association between blood pressure levels and risk of stroke in patients with atrial fibrillation: results from a prospective registry in Xinjiang, China

  • By

  • Bizhong Che

  • Meidina Yeerken

  • Kangting Luo

  • Wen Peng

  • Meng Wei

  • Xu Yang

  • Yanmei Lu

  • Xianhui Zhou

  • Hua Wang

  • Fubing Ma

  • Yunguo Chen

  • Youfa Wang

  • Baopeng Tang

  • May 29, 2026

  • 0 min

Share

Link Between Blood Pressure Measurements and Stroke Risk in Atrial Fibrillation Patients

Overview

This study investigates the association between blood pressure levels at hospital admission and the risk of in-hospital stroke in patients with atrial fibrillation. Elevated blood pressure was found to be independently associated with a higher risk of stroke, emphasizing the need for effective blood pressure management in this population.

Background

Atrial fibrillation (AF) is a prevalent cardiac rhythm disorder that significantly increases stroke risk. Hypertension, a common comorbidity in AF patients, is a critical factor in stroke risk assessment and management. Understanding the relationship between blood pressure levels and stroke risk during hospitalization is essential for optimizing acute care strategies.

Data Highlights

Blood Pressure Category (SBP/DBP)Odds Ratio (95% CI)
<120/80 mmHg1.00
140–159/90–99 mmHg1.27 (1.16–1.39)
160–179/100–109 mmHg1.26 (1.11–1.45)
>=180/110 mmHg1.76 (1.44–2.15)

Key Findings

  • Elevated blood pressure levels are associated with an increased risk of stroke in patients with atrial fibrillation.
  • Linear dose-response relationships exist between both systolic and diastolic blood pressure and stroke risk.
  • Adding blood pressure measurements to conventional risk factors enhances stroke risk prediction.
  • Multivariable-adjusted odds ratios indicate significant stroke risk at various blood pressure thresholds.
  • Subgroup analyses confirm the robustness of the association between blood pressure and stroke risk.

Clinical Implications

Effective management of elevated blood pressure in atrial fibrillation patients is crucial to reduce the risk of in-hospital stroke. Clinicians should prioritize blood pressure control as part of comprehensive care strategies during hospitalization.

Conclusion

The findings highlight the importance of monitoring and managing blood pressure levels in patients with atrial fibrillation to mitigate stroke risk during hospitalization.

Related Resources & Content

  1. Frontiers in Cardiovascular Medicine, 2026 -- Bidirectional relationships between increased arterial stiffness and atrial fibrillation
  2. European Journal of Preventive Cardiology, 2026 -- Ethnic differences in clinical outcomes following major bleeding in atrial fibrillation patients
  3. Frontiers in Endocrinology, 2026 -- The role of albumin–globulin ratio in peripheral arterial disease among hypertensive adults
  4. Frontiers in Neurology, 2026 -- Blood pressure variability plays a critical role in determining the prognosis of acute ischemic stroke combined with hypertension
  5. 2024 ESC Guidelines for Management of Atrial Fibrillation: Key Points - American College of Cardiology
  6. Blood pressure and in-hospital outcomes in patients hospitalized with atrial fibrillation: findings from the CCC-AF project | Hypertension Research
  7. 2024 ESC Guidelines for Management of Atrial Fibrillation: Key Points - American College of Cardiology
  8. Blood pressure and in-hospital outcomes in patients hospitalized with atrial fibrillation: findings from the CCC-AF project | Hypertension Research

Original Source(s)

Related Content