Hormonal Birth Control Might Reduce Female Athletes’ ACL Tears - Report - MDSpire

Hormonal Birth Control Might Reduce Female Athletes’ ACL Tears

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  • March 4, 2025

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Clinical Report: Hormonal Birth Control Might Reduce Female Athletes’ ACL Tears

Overview

A study at Cedars-Sinai suggests that hormonal birth control may reduce ACL injury risk in female athletes by lowering relaxin levels, which contribute to ligament looseness. The research indicates that athletes using hormonal contraception exhibited improved knee and hip mechanics during landing.

Background

Female athletes face a significantly higher risk of ACL tears compared to males, particularly after age 14. Understanding the role of hormones, such as relaxin, in ligament stability is crucial as more women participate in competitive sports. This study explores whether hormonal birth control can mitigate this injury risk.

Data Highlights

Study GroupInjury IncidenceRelaxin Levels
Hormonal Birth Control UsersLowerLow
Non-UsersHigherHigh

Key Findings

  • Female athletes are 2-8 times more likely to sustain ACL injuries than males.
  • Relaxin, a hormone that increases ligament looseness, peaks in the second half of the menstrual cycle.
  • Athletes on hormonal birth control demonstrated improved knee and hip mechanics during landing.
  • Lower relaxin levels in hormonal birth control users correlated with fewer injuries.
  • The study involved 72 high-level collegiate athletes, with 32 using hormonal birth control.

Clinical Implications

Clinicians should consider the potential benefits of hormonal birth control in reducing ACL injury risk among female athletes. However, further research is needed to establish definitive recommendations, as current guidelines emphasize neuromuscular training as the primary preventive measure.

Conclusion

The findings from this study suggest a possible protective effect of hormonal birth control against ACL injuries in female athletes, warranting further investigation into its clinical application.

References

  1. Trentacosta NE, Schimmoeller NR, Cedars-Sinai, 2023 -- Hormonal Birth Control Might Reduce Female Athletes’ ACL Tears
  2. Paska J, Watson SL, Larrabee GA, Ndjonko LC, Tjong VK, 2026 -- Has the Protective Effect of Hormonal Contraception Been Overestimated?
  3. Knee Surgery, Sports Traumatology, Arthroscopy, 2021 -- Higher Incidence of ACL Injuries Among Football Players Transitioning to New Coaches
  4. Knee Surgery, Sports Traumatology, Arthroscopy, 2018 -- The Role of Force Timing Over Magnitude in Explaining Gender Differences in ACL Injury Risk
  5. Knee Surgery, Sports Traumatology, Arthroscopy, 2021 -- Identifying Modifiable Risk Factors for First-time Anterior Cruciate Ligament Injuries in Adolescent Female Elite Athletes
  6. Knee Surgery, Sports Traumatology, Arthroscopy — Male Athletes Exhibit Higher Knee Frontal Moments Than Female Athletes During Cutting Maneuvers' Impact Phase, Despite Age-Related Increases in Females
  7. National Athletic Trainers’ Association Position Statement
  8. Has the Protective Effect of Hormonal Contraception Been Overestimated? A Systematic Review and Meta-analysis of Oral Contraceptive Pills and ACL Injury - Julie Paska, Samantha L. Watson, Grace A. Larrabee, Laura C.M. Ndjonko, Vehniah K. Tjong, 2026

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