A methodological review of acupuncture for chronic atrophic gastritis: toward a core outcome set - Report - MDSpire

A methodological review of acupuncture for chronic atrophic gastritis: toward a core outcome set

  • By

  • Han Zhang

  • Yang Yu

  • Siyi Zheng

  • Shuaiyu Ying

  • Ding Shen

  • Wei Ye

  • Yichun Shi

  • Chenben Zhang

  • Xiaojing Wang

  • Yi Liang

  • June 1, 2026

  • 0 min

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Clinical Report: A Systematic Review of Acupuncture's Efficacy in Chronic Atrophic Gastritis

Overview

This systematic review evaluates the efficacy of acupuncture for chronic atrophic gastritis (CAG) through an analysis of 55 randomized controlled trials (RCTs).

Background

Chronic atrophic gastritis is a precancerous condition that can progress to gastric cancer, making timely diagnosis and intervention crucial. The rising incidence of CAG necessitates effective treatment options, with acupuncture being studied as a therapy.

Data Highlights

No standardized numerical data available.

Key Findings

  • 55 RCTs involving 5,311 patients were reviewed.
  • 83.6% of studies employed low-risk randomization methods.
  • Only 3.6% implemented allocation concealment and 1.8% used blinding.
  • 57 different outcome indicators were reported, with a predominance of laboratory and imaging examinations (55.4%).
  • 34.5% of studies did not mention ethical approval.
  • There was considerable heterogeneity in outcome measures.

Clinical Implications

Standardized clinical trial protocols and a core outcome set for acupuncture research in CAG are needed.

Conclusion

The review identifies gaps in the methodological quality of acupuncture studies for CAG.

Related Resources & Content

  1. Frontiers in Medicine, 2026 -- A methodological Review of Acupuncture for Chronic Atrophic Gastritis: Toward A Core Outcome Set
  2. Obesity Surgery — Alleviation of Postoperative Pain Following Laparoscopic Bariatric Surgery Through Customized Checkpoint Acupuncture—Findings from a STRICTA Compliant Pilot Study
  3. Frontiers in Medicine — Core acupoint selection strategies and multifactorial analysis for acute musculoskeletal pain
  4. Frontiers in Oncology — Effectiveness of acupuncture for cancer-related fatigue: a systematic reviews and meta-analysis
  5. Frontiers in Medicine — Adjunctive acupuncture for sepsis-associated acute gastrointestinal injury: a systematic review, meta-analysis, and exploratory Bayesian network meta-analysis
  6. 2025 European MAPS III guideline update
  7. ACG Clinical Guideline on Gastric Premalignant Conditions
  8. Assessing gastric cancer risk using the OLGA and OLGIM systems in Republic of Moldova
  9. Frontiers | A methodological Review of Acupuncture for Chronic Atrophic Gastritis: Toward A Core Outcome Set
  10. Acupuncture therapy for atrophic gastritis with upper gastrointestinal symptoms: A systematic review and network meta-analysis - ScienceDirect
  11. Study Details | NCT07152860 | Evaluation of the Efficacy of Electroacupuncture in the Treatment of Chronic Atrophic Gastritis | ClinicalTrials.gov

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