Clinical Report: Height Development in Danish Transgender Youth Undergoing Hormonal Therapy
Overview
This erratum clarifies that height measurements reported in the study refer to the last recorded heights rather than final adult heights in Danish transgender youth undergoing GnRH analog and hormonal therapy. The corrected data indicate that most trans girls and trans boys had heights within ±2 standard deviations (SD) of their respective cisgender reference populations at last measurement.
Background
Transgender youth undergoing puberty suppression with GnRH analogs followed by gender-affirming hormone therapy experience alterations in growth trajectories. Monitoring height development is crucial to understand the impact of these treatments on final stature. Previous reports have assessed adult height outcomes compared to cisgender reference populations, but precise terminology regarding timing of height measurement is essential for accurate interpretation.
Data Highlights
Height data from the cohort showed: 6 out of 55 trans girls (11%) had last recorded heights above +2 SD compared to cis girls; 155 out of 164 trans boys (95%) had last recorded heights within ±2 SD for cis girls; and 78 out of 164 trans boys (48%) had last recorded heights below −2 SD for cis boys.
Key Findings
All trans girls except one had last recorded heights within ±2 SD for cis boys.
Height SDS trajectories declined during GnRHa treatment and increased for some after starting estradiol.
11% of trans girls had last recorded heights above +2 SD compared to cis girls.
95% of trans boys had last recorded heights within ±2 SD for cis girls.
Height SDS trajectories in trans boys did not change during hormone therapy.
Nearly half (48%) of trans boys had last recorded heights below −2 SD for cis boys.
Clinical Implications
Clinicians should interpret height data in transgender youth with awareness that reported measurements may reflect last recorded rather than final adult heights. Monitoring growth trajectories during GnRHa and hormone therapy remains important to anticipate stature outcomes and counsel patients accordingly.
Conclusion
The correction emphasizes precise terminology regarding height measurement timing, ensuring accurate understanding of growth patterns in transgender youth undergoing hormonal treatment.
