The Transdiagnostic Oncology Program (TOP): A Comprehensive Lifestyle Intervention Aimed at Enhancing Quality of Life for Cancer Survivors - A Pilot Study with Pre- and Post-Intervention Analysis in Primary Care - Report - MDSpire

The Transdiagnostic Oncology Program (TOP): A Comprehensive Lifestyle Intervention Aimed at Enhancing Quality of Life for Cancer Survivors - A Pilot Study with Pre- and Post-Intervention Analysis in Primary Care

  • By

  • Sanne H. Booij

  • Amy Pieper

  • Christianne D. Wester

  • Ute Bültmann

  • Elkana C. Waarsenburg

  • H. J. Rogier Hoenders

  • November 10, 2025

  • 0 min

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Clinical Report: The Transdiagnostic Oncology Program (TOP) Pilot Study

Overview

The Transdiagnostic Oncology Program (TOP) is a 12-month interdisciplinary lifestyle intervention aimed at improving the quality of life for cancer survivors. Preliminary results indicate feasibility and positive impacts on quality of life, addressing common clinical problems such as fatigue, anxiety, and depression.

Background

Incorporate statistics and references for psychological and physical impairments.

Data Highlights

Detail the specific improvements in quality of life and the transdiagnostic issues addressed.

Key Findings

Verify and clarify the source of the fatigue statistic and ensure all findings are data-supported.

Clinical Implications

Healthcare providers should consider implementing interdisciplinary aftercare programs like TOP to address the complex needs of cancer survivors. Such programs may improve quality of life and support survivors in returning to productive work life.

Conclusion

Highlight the necessity for larger trials and specify areas for further research.

References

  1. Beumeler et al., Pilot Study, Year -- Transdiagnostic Oncology Program
  2. American Cancer Society, ACS Guidelines, 2025 -- Nutrition and Physical Activity for Survivors
  3. NEJM, CHALLENGE Trial, 2025 -- Structured Exercise after Adjuvant Chemotherapy
  4. The ASCO Post — Expert Point of View: Debu Tripathy, MD Related Articles
  5. The ASCO Post — Update on Lifestyle, Exercise, and Nutrition Early After Diagnosis (LEANer) Trial in Patients With Breast Cancer
  6. The ASCO Post — Digital Integrative Medicine Intervention for Patients Undergoing Active Cancer Treatment
  7. The ASCO Post — Update on Lifestyle, Exercise, and Nutrition Early After Diagnosis (LEANer) Trial in Patients With Breast Cancer Guest Editor
  8. Expert Point of View: Debu Tripathy, MD
  9. Update on LEANer Trial in Patients With Breast Cancer
  10. Digital Integrative Medicine Intervention for Patients Undergoing Active Cancer Treatment
  11. American Cancer Society Guideline for Diet and Physical Activity for Cancer Survivors | American Cancer Society
  12. Structured Exercise after Adjuvant Chemotherapy for Colon Cancer | MMS/NEJM Continuing Education Center
  13. A meta-analysis of healthy lifestyle interventions addressing quality of life of cancer survivors in the post treatment phase - PubMed

Original Source(s)

The Transdiagnostic Oncology Program (TOP): A Comprehensive Lifestyle Intervention Aimed at Enhancing Quality of Life for Cancer Survivors - A Pilot Study with Pre- and Post-Intervention Analysis in Primary Care

  • by Sanne H. Booij, Amy Pieper, Christianne D. Wester, Ute Bültmann, Elkana C. Waarsenburg, H. J. Rogier Hoenders

  • November 10, 2025

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