Metastatic malignant melanoma presenting as bilateral acute mastitis in a lactating woman: a case report and literature review - Report - MDSpire

Metastatic malignant melanoma presenting as bilateral acute mastitis in a lactating woman: a case report and literature review

  • By

  • Zilin Wang

  • Shaowu Zeng

  • Qiaorong Zhou

  • Jujiang Guo

  • July 6, 2026

  • 0 min

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Clinical Report: Bilateral Acute Mastitis in a Lactating Woman as a Presentation of Metastatic Malignant Melanoma

Overview

This case report describes a 36-year-old postpartum woman who presented with bilateral breast swelling and erythema, initially diagnosed as severe lactational mastitis. Further evaluation revealed diffusely metastatic malignant melanoma originating from a previously excised benign nevus.

Background

Malignant melanoma is known for its high metastatic potential, with breast metastasis being rare. This case illustrates how metastatic melanoma can mimic benign inflammatory conditions, especially in the postpartum period.

Data Highlights

No numerical data or trial data available in the source material.

Key Findings

  • Bilateral breast involvement from metastatic melanoma is exceptionally rare.
  • The patient was initially misdiagnosed with severe lactational mastitis.
  • Metastatic melanoma can present as a benign inflammatory condition in postpartum women.
  • The patient exhibited a rapidly progressive disease course.
  • A high index of suspicion is necessary for atypical breast presentations in patients with a history of malignancy.

Clinical Implications

This case emphasizes the importance of thorough history-taking and examination of prior skin lesions in patients presenting with atypical breast symptoms.

Conclusion

The case highlights the diagnostic challenges posed by metastatic melanoma in the breast, particularly in postpartum women.

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