Development and internal validation of a nomogram to predict perioperative hypothermia in patients undergoing laparoscopic gynecologic surgery under general anesthesia: a retrospective cohort study - Report - MDSpire

Development and internal validation of a nomogram to predict perioperative hypothermia in patients undergoing laparoscopic gynecologic surgery under general anesthesia: a retrospective cohort study

  • By

  • Yingbo Ren

  • Lei Huang

  • Ling Chen

  • Feng Liu

  • Lihong Song

  • Qingyuan Li

  • Xin Wang

  • Hongyan Li

  • June 10, 2026

  • 0 min

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Clinical Report: Nomogram for Forecasting Perioperative Hypothermia

Overview

This study developed and validated a nomogram to predict perioperative hypothermia in patients undergoing laparoscopic gynecologic surgery under general anesthesia. The model demonstrated good discrimination and calibration, highlighting its potential utility in clinical practice.

Background

Perioperative hypothermia is a prevalent complication in laparoscopic gynecologic surgery, associated with adverse outcomes such as surgical site infections and prolonged hospital stays. Accurate prediction tools are essential for identifying at-risk patients and implementing preventive strategies. This study addresses the gap in individualized prediction methods for perioperative hypothermia.

Data Highlights

ParameterTraining Cohort (n=294)Validation Cohort (n=130)
AUC0.788 (95% CI, 0.732–0.843)0.810 (95% CI, 0.727–0.893)
Sensitivity0.6230.925
Specificity0.8530.580

Key Findings

  • 65.8% of patients developed perioperative hypothermia.
  • Key predictors included age, body mass index, and operative time.
  • The nomogram achieved an AUC of 0.788 in the training cohort and 0.810 in the validation cohort.
  • Bootstrap validation yielded an optimism-corrected AUC of 0.776.
  • At the Youden cutoff, the model's sensitivity and specificity varied between cohorts.

Clinical Implications

The nomogram can assist clinicians in identifying patients at high risk for perioperative hypothermia, enabling targeted interventions such as intensified temperature monitoring and active warming strategies. Its implementation may improve patient outcomes in laparoscopic gynecologic surgery.

Conclusion

The developed nomogram represents a promising tool for predicting perioperative hypothermia, warranting further external validation before widespread clinical adoption.

Related Resources & Content

  1. Innovative Air Conditioning Approach for Operating Rooms to Reduce Patient Hypothermia and Surgeon Overheating: A Historical Control Study, Surgical Endoscopy, 2019 -- Title
  2. The Use of Warm, Humidified Insufflation Gas in Gynecologic Laparoscopic Surgery Alleviates Postoperative Pain in Susceptible Patients: A Randomized, Multi-Arm Study, Surgical Endoscopy, 2021 -- Title
  3. A nomogram for predicting free flap necrosis in soft tissue reconstruction of lower limbs: a retrospective cohort study, Frontiers in Medicine, 2026 -- Title
  4. Effects of Different intraoperative warming strategies on Hypothermia and Postoperative Coagulation Function in Severely Injured Emergency Surgery Patients, Frontiers in Medicine, 2026 -- Title
  5. Guideline for Patient Temperature Management, AORN, 2025 -- Title
  6. Updated risk prediction model for perioperative hypothermia in adults: A systematic review and meta-analysis, ScienceDirect, 2025 -- Title
  7. Guideline for Patient Temperature Management
  8. Updated risk prediction model for perioperative hypothermia in adults: A systematic review and meta-analysis - ScienceDirect

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