Global trends and neurobiological frontiers of manual therapy in sleep disorders: integrating bibliometrics with clinical evidence - Report - MDSpire

Global trends and neurobiological frontiers of manual therapy in sleep disorders: integrating bibliometrics with clinical evidence

  • By

  • Yixiang Wang

  • Donghai Wu

  • Yingjun Liu

  • Siying Qu

  • Yutian Chen

  • Huiqin Chu

  • Haiju Sun

  • Xiaoyu Li

  • June 24, 2026

  • 0 min

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Clinical Report: Worldwide Patterns and Neurobiological Advances in Manual Therapy for Sleep Disorders

Overview

This bibliometric analysis reveals a growing body of research on manual therapy as a non-pharmacological intervention for sleep disorders.

Background

Sleep disorders significantly impact both nocturnal rest and daytime functioning, contributing to emotional dysregulation and adverse mental health outcomes. The increasing prevalence of sleep disorders has prompted interest in complementary and alternative medicine, particularly manual therapy, as a potential treatment option.

Data Highlights

Publication CountInstitutionsCountries
59432163

Key Findings

  • Manual therapy is gaining recognition as a complementary treatment for sleep disorders.
  • Research shows a consistent annual increase in publications and citation impact related to manual therapy.
  • Key research areas include neurobiological mechanisms and circadian rhythm regulation.

Clinical Implications

Clinicians should consider integrating manual therapy into treatment plans while remaining aware of the need for further validation through rigorous clinical trials.

Conclusion

The evolving research landscape indicates that research on manual therapy for sleep disorders is evolving toward multidimensional and interdisciplinary integration.

Related Resources & Content

  1. npj Digital Medicine, 2026 -- Advancing Comprehensive Sleep Health: The Role of Multimodal AI in the Hang Hao Meng Agent
  2. npj Digital Medicine, 2026 -- Customized Intracranial Sleep Stage Decoding During Deep Brain Stimulation: A Study of Supervised and Unsupervised Approaches
  3. Frontiers in Psychiatry, 2026 -- Research advances in physical activity and insomnia: a bibliometric and thematic evolution analysis
  4. Frontiers in Psychiatry, 2026 -- Non-invasive electrical stimulation for sleep disturbances in adults: protocol for an evidence−mapping umbrella review of systematic reviews and meta−analyses with subgroup analysis by intervention type and population
  5. AASM, 2025 -- Combination Treatment for Chronic Insomnia Disorder in Adults
  6. BMC Complementary Medicine and Therapies, 2025 -- Massage positively influences daytime brain activity and reduces arousal state in poor sleepers: a randomized controlled trial
  7. Frontiers in Neurology, 2024 -- Efficacy of non-pharmacological interventions on sleep quality in patients with cancer-related insomnia: a network meta-analysis
  8. https://aasm.org/wp-content/uploads/2025/06/Combination-Treatment-for-Chronic-Insomnia-Disorder-in-Adults-CPG-public-comment-period.pdf
  9. Massage positively influences daytime brain activity and reduces arousal state in poor sleepers: a randomized controlled trial | BMC Complementary Medicine and Therapies | Springer Nature Link
  10. Efficacy of non-pharmacological interventions on sleep quality in patients with cancer-related insomnia: a network meta-analysis

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