Economic Evaluation and Resource Use in Thoracentesis and Paracentesis for Patients with Gynecologic Cancers
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By
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Yingao Zhang
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Olivia Foy
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Grace Pipes
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Margaret I. Liang
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July 21, 2026
Economic Evaluation and Resource Use in Thoracentesis and Paracentesis
Overview
This study evaluates the frequency and costs associated with unindicated laboratory tests on paracentesis and thoracentesis specimens from patients with gynecologic cancers.
Background
Paracentesis and thoracentesis are frequently performed procedures in patients with advanced gynecologic cancers experiencing ascites or pleural effusions. Understanding the patterns of unindicated testing can inform future evaluations.
Data Highlights
| Procedure Type | Total Procedures | Unindicated Tests (%) |
|---|---|---|
| Paracentesis | 665 | 79 |
| Thoracentesis | 311 | 79 |
Key Findings
- 216 patients with gynecologic cancers were analyzed.
- 78% of patients underwent at least one paracentesis; 45% underwent at least one thoracentesis.
- 40% of procedures had laboratory test results sent, with 79% of these containing at least one unindicated test.
- The total cost from unindicated laboratory tests was $1,129,520.
- Non-oncology clinicians had higher odds of ordering unindicated tests compared to oncology clinicians.
Clinical Implications
Clinicians should evaluate the necessity of laboratory tests for paracentesis and thoracentesis in patients with established cancer diagnoses.
Conclusion
The study reveals a prevalence of unindicated laboratory testing in procedures for patients with gynecologic cancers.
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Based on findings from:
Cost Analysis and Resource Utilization of Gynecologic Cancer-Related Thoracenteses and Paracenteses
Yingao Zhang, Olivia Foy, Grace Pipes, Margaret I. Liang. Jama Network Open, 2026.
https://jamanetwork.com/journals/jamanetworkopen/fullarticle/2851867
This content is an AI-generated, fully rewritten summary based on a published scholarly article. It does not reproduce the original text and is not a substitute for the original publication. Readers are encouraged to consult the source for full context, data, and methodology.