Sex differences in inappropriate imaging requests: insights from the Medical Imaging Decision And Support (MIDAS) study - Report - MDSpire

Sex differences in inappropriate imaging requests: insights from the Medical Imaging Decision And Support (MIDAS) study

  • By

  • Stijntje Willemijn Dijk

  • Claudia Wollny

  • Thomas Kroencke

  • M. G. Myriam Hunink

  • November 6, 2025

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Gender Variations in Unwarranted Imaging Requests: MIDAS Trial Findings

Overview

This study from the MIDAS trial reveals significant sex-based differences in the appropriateness of diagnostic imaging requests in German academic hospitals. Women and men differ in the likelihood of receiving imaging deemed inappropriate, highlighting potential disparities in clinical decision-making.

Background

Diagnostic imaging is critical for accurate diagnosis and treatment but is often overutilized, leading to unnecessary radiation exposure and increased healthcare costs. Factors influencing inappropriate imaging include clinical uncertainty, medico-legal concerns, and physician adherence to guidelines. Sex differences in healthcare delivery are well documented, with emerging evidence suggesting women and men experience disparities in imaging utilization and appropriateness. Prior studies have been limited in scope, prompting this comprehensive evaluation using the ESR iGuide within the MIDAS trial.

Data Highlights

CountryFemale Appropriateness (%)Male Appropriateness (%)
Belgium7181
Estonia6572
Greece5560
Slovenia7791
Denmark8884
Finland8078
Hungary7774

Key Findings

  • Women are more likely than men to receive certain imaging tests without clear clinical risk differences, such as venous ultrasonography for suspected deep vein thrombosis.
  • Women undergo diagnostic imaging more frequently for conditions like lower back pain, whereas men are more often recommended surgical interventions.
  • Women with ischemic stroke experience longer emergency room delays not explained by clinical factors.
  • Sex-based disparities in imaging appropriateness vary by country, with some showing lower appropriateness rates in females and others showing the opposite.
  • The MIDAS trial used the ESR iGuide to systematically assess imaging appropriateness, revealing sex-related differences in German academic hospitals.

Clinical Implications

Clinicians should be aware of potential unconscious biases and systemic factors contributing to sex-based disparities in imaging appropriateness. Incorporating decision support tools like the ESR iGuide may help standardize imaging requests and reduce unwarranted variations. Tailoring imaging decisions to clinical guidelines while considering sex-specific presentations can improve diagnostic accuracy and resource utilization.

Conclusion

The MIDAS trial highlights important sex-based differences in the appropriateness of diagnostic imaging requests, underscoring the need for targeted interventions to ensure equitable and guideline-concordant imaging practices. Further research is warranted to explore underlying causes and optimize clinical decision-making.

References

  1. Singer et al 2023 -- CT Scan Appropriateness Using ESR iGuide Across Countries
  2. MIDAS Trial Protocol and Ethics Approvals 2021-2023
  3. American College of Radiology Appropriateness Criteria and ESR iGuide Adaptation

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