Long-term epidemiological patterns of pediatric infectious diseases in an urban district of Shanghai, 2015–2023 - Report - MDSpire

Long-term epidemiological patterns of pediatric infectious diseases in an urban district of Shanghai, 2015–2023

  • By

  • Hong Tong

  • Huizhen Wang

  • Chenxi Wang

  • Xingyu Chen

  • Biao Meng

  • Shujun Zeng

  • Chenyan Jiang

  • Ziyu Qian

  • May 29, 2026

  • 0 min

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Clinical Report: Epidemiological Trends of Pediatric Infectious Diseases in Shanghai

Overview

This longitudinal study from 2015 to 2023 reveals significant trends in pediatric infectious diseases in Xuhui District, Shanghai, highlighting a decline in incidence until 2021 followed by a sharp increase attributed mainly to COVID-19 notifications. The findings underscore the need for targeted prevention strategies as disease patterns shift post-pandemic.

Background

Pediatric infectious diseases are a leading cause of morbidity and mortality, particularly in urban settings where children frequently interact in high-contact environments. The COVID-19 pandemic has altered the epidemiological landscape, with potential implications for immunity and disease transmission. Understanding these trends is crucial for developing effective public health strategies.

Data Highlights

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Key Findings

  • Total of 27,940 pediatric cases reported from 2015 to 2023.
  • Average annual incidence of 2,421.68 per 100,000 children.
  • Significant decline in incidence from 2015 to 2021 (APC = -11.71%).
  • Sharp increase in incidence post-2021 primarily due to COVID-19 notifications (APC = 141.05%).
  • Age distribution shifted towards school-aged children, with significant increases in cases among those aged ≥4 years.
  • Distinct trends observed for specific diseases, with influenza surging post-pandemic while varicella and mumps continued to decline.

Clinical Implications

Healthcare providers should be aware of the changing epidemiological patterns of pediatric infectious diseases, particularly the impact of COVID-19 on disease notifications. Targeted vaccination and surveillance strategies are essential to mitigate the risk of outbreaks and protect vulnerable populations.

Conclusion

The study highlights significant shifts in pediatric infectious disease trends in Xuhui District, emphasizing the need for ongoing surveillance and tailored public health interventions in the post-pandemic landscape.

Related Resources & Content

  1. Frontiers in Pediatrics, 2026 -- Epidemiological analysis of six common respiratory pathogen infections in children in Chengdu from 2022 to 2024
  2. Frontiers in Pediatrics, 2026 -- Analysis of the epidemic situation of respiratory pathogens in central and southern China before and after the COVID-19 pandemic
  3. conexiant -- Hospital-based Clinical Surveillance and Pediatric Diseases
  4. Western Pacific Health Data Platform -- Continued increase in measles cases in the Western Pacific Region
  5. Infection — Inadequate Efficacy of Pneumococcal Vaccines Against Emerging Strains of Streptococcus pneumoniae Serotype 14/ST876
  6. Evolutionary Diversity of Coxsackievirus A6 Causing Severe Hand, Foot, and Mouth Disease
  7. Continued increase in measles cases in the Western Pacific Region | Western Pacific Health Data Platform
  8. Real-world effectiveness of nirsevimab against respiratory syncytial virus disease in infants: a systematic review and meta-analysis - ScienceDirect

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