Clinical Report: Assessment of an Online Clinical Tool for Estimating BPD Risk

Overview

This study evaluates the predictive performance of the NICHD BPD Outcome Estimator in a cohort of extremely preterm infants.

Background

Bronchopulmonary dysplasia (BPD) is a significant complication in extremely preterm infants. The NICHD BPD Outcome Estimator aims to provide clinicians with a tool to assess risk based on clinical data.

Data Highlights

Key Findings

• The NICHD BPD Outcome Estimator demonstrated an AUC of 0.71 on postnatal day 7.
• The AUC improved to 0.76 on postnatal day 14.
• Variable predictive accuracy was observed across different postnatal time points.

Clinical Implications

Clinicians should integrate the NICHD BPD Outcome Estimator's predictions with clinical judgment.

Conclusion

The NICHD BPD Outcome Estimator shows moderate accuracy in predicting BPD outcomes.

Related Resources & Content

1. Frontiers in Pediatrics, 2026 -- A nomogram for predicting the risk of bronchopulmonary dysplasia in preterm infants: a prospective multicenter study
2. Frontiers in Pediatrics, 2026 -- Respiratory trajectory and risk of death or moderate-to-severe bronchopulmonary dysplasia in very preterm infants: a nine-year cohort study
3. Frontiers in Pediatrics, 2026 -- Integration of miRNA profiles and clinical data for early risk assessment of bronchopulmonary dysplasia in VLBW and ELBW newborn infants: a discovery study
4. BMJ Paediatrics Open, 2023 -- Healthcare burden of bronchopulmonary dysplasia among very preterm infants in China: a cohort study
5. The Diagnosis of Bronchopulmonary Dysplasia in Very Preterm Infants. An Evidence-based Approach - PMC, 2023
6. European Consensus Guidelines on the Management of Respiratory Distress Syndrome: 2022 Update - PMC, 2023
7. The Diagnosis of Bronchopulmonary Dysplasia in Very Preterm Infants. An Evidence-based Approach - PMC
8. European Consensus Guidelines on the Management of Respiratory Distress Syndrome: 2022 Update - PMC
9. https://www.plusstrial.org/media/e41b14os/pluss-jama-2024.pdf