Nurse-evaluated intrinsic capacity predicts rehospitalization risk in coronary artery disease patients post-percutaneous coronary intervention - Report - MDSpire

Nurse-evaluated intrinsic capacity predicts rehospitalization risk in coronary artery disease patients post-percutaneous coronary intervention

  • By

  • Yuning Zhao

  • Wenwen Zhang

  • Jing Yang

  • Yuqi Fang

  • Yizhu Yan

  • Guangyao Zhai

  • April 20, 2026

  • 0 min

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Clinical Report: Nurse-evaluated intrinsic capacity predicts rehospitalization risk

Overview

This study demonstrates that a higher intrinsic capacity (IC) score is significantly associated with increased all-cause and cardiovascular rehospitalization risk in patients with coronary artery disease (CAD) following percutaneous coronary intervention (PCI). The findings suggest that IC can serve as a valuable tool for predicting rehospitalization outcomes in this population.

Background

Coronary artery disease (CAD) poses a significant burden on patients and healthcare systems, with high rates of rehospitalization following PCI. Identifying patients at risk for readmission is crucial for improving long-term outcomes and quality of life. The concept of intrinsic capacity (IC) offers a new perspective on patient health, focusing on functional ability rather than solely on disease presence.

Data Highlights

OutcomeHazard Ratio (HR)95% Confidence Interval (CI)
All-cause rehospitalization (IC = 4 vs IC = 0)3.071.89–5.00
Cardiovascular rehospitalization (IC = 4 vs IC = 0)5.232.30–11.89
AUC for all-cause rehospitalization-0.692 (0.664–0.729)

Key Findings

  • A higher IC score is independently associated with increased all-cause rehospitalization risk.
  • IC score predicts cardiovascular rehospitalization risk with a significant hazard ratio.
  • The relationship between IC score and rehospitalization risk is consistent across different lesion morphologies and revascularization strategies.
  • IC score does not significantly predict non-cardiovascular rehospitalization.
  • Receiver operating characteristic (ROC) analysis indicates moderate predictive performance for all-cause rehospitalization.

Clinical Implications

Healthcare providers should consider incorporating IC assessments into routine evaluations for CAD patients post-PCI to identify those at higher risk for rehospitalization. Early interventions based on IC scores may improve patient outcomes and reduce healthcare utilization.

Conclusion

The study highlights the importance of intrinsic capacity as a predictive tool for rehospitalization in CAD patients following PCI, suggesting that functional assessments can enhance risk stratification and patient management.

References

  1. Clinical Research in Cardiology, 2023 -- Impact of Coronary No-Reflow on Clinical Outcomes
  2. Basic Research in Cardiology, 2014 -- Effects of Repeated Balloon Inflation During Primary Percutaneous Coronary Intervention
  3. Clinical Research in Cardiology, 2024 -- Utilizing the Echocardiographic Killip Score to Forecast Hospital Readmissions
  4. Clinical Research in Cardiology, 2024 -- Factors Influencing Symptom Relief in Chronic Coronary Syndrome Patients
  5. 2025 ACC/AHA Guideline for the Management of Patients With Acute Coronary Syndromes, American College of Cardiology
  6. Intrinsic capacity transitions predict overall and cause-specific mortality, PubMed
  7. New, Expanded ICOPE Handbook from WHO, GlobalAgeing
  8. 2025 ACC/AHA Guideline for the Management of Patients With Acute Coronary Syndromes
  9. Intrinsic capacity transitions predict overall and cause-specific mortality, incident disability, and healthcare utilization - PubMed
  10. New, Expanded ICOPE Handbook from WHO is a Resource to Support Health Workers Worldwide - GlobalAgeing

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