Clinical outcomes of tibial cortex transverse transport versus antibiotic-loaded bone cement for Wagner grade 3–4 diabetic foot ulcers: a real-world retrospective cohort study - Report - MDSpire

Clinical outcomes of tibial cortex transverse transport versus antibiotic-loaded bone cement for Wagner grade 3–4 diabetic foot ulcers: a real-world retrospective cohort study

  • By

  • Muhan Li

  • Chenghao Zhu

  • Zhongxian Xu

  • Xiwen Feng

  • Guangming Zheng

  • Yongjun Li

  • June 3, 2026

  • 0 min

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Comparative Analysis of Tibial Cortex Transverse Transport and ALBC for DFUs

Overview

{'add': "Define metrics for 'superior outcomes'."}

Background

Diabetic foot ulcers are a significant cause of non-traumatic lower-extremity amputations, especially in patients with advanced grades like Wagner grade 3–4. Effective management is critical due to the complexities of infection and perfusion issues. Understanding the comparative effectiveness of surgical strategies like TTT and ALBC can guide clinicians in optimizing treatment for these challenging cases.

Data Highlights

{'clarify': "Provide definitions for 'Not specified' outcomes."}

Key Findings

{'expand': 'Include clinical relevance of findings.'}

Clinical Implications

{'emphasize': 'Highlight individualized treatment importance.'}

Conclusion

{'add': 'Mention need for further research.'}

Related Resources & Content

  1. IWGDF/IDSA Guidelines on the Diagnosis and Treatment of Diabetes-Related Foot Infections
  2. Frontiers | Efficacy and safety of antibiotic-loaded bone cement in the treatment of diabetic foot: a systematic review and meta-analysis
  3. A Systematic Review on Tibial Cortex Transverse Transport in the Treatment of Ischemic Ulcers of the Lower Limb
  4. Frontiers in Surgery — Staged antibiotic-loaded cement-based reconstruction versus flap-based reconstruction for complex diabetic foot defects in patients with osteoporosis: a retrospective cohort study
  5. Knee Surgery, Sports Traumatology, Arthroscopy — Bone Microstructure of Anterior Cruciate Ligament Footprints Remains Consistent Post-Reconstruction and Does Not Influence Long-Term Outcomes
  6. Infection — The Impact of Bacterial Presence and Sampling Techniques on Outcomes in Diabetic Foot Infections
  7. Outcomes of Tibial Plateau Fractures Managed with Bone Allograft: A Radiographic and Clinical Analysis
  8. IWGDF/IDSA Guidelines on the Diagnosis and Treatment of Diabetes-Related Foot Infections
  9. A Systematic Review on Tibial Cortex Transverse Transport in the Treatment of Ischemic Ulcers of the Lower Limb
  10. Frontiers | Efficacy and safety of antibiotic-loaded bone cement in the treatment of diabetic foot: a systematic review and meta-analysis

Original Source(s)

Clinical outcomes of tibial cortex transverse transport versus antibiotic-loaded bone cement for Wagner grade 3–4 diabetic foot ulcers: a real-world retrospective cohort study

  • by Muhan Li, Chenghao Zhu, Zhongxian Xu, Xiwen Feng, Guangming Zheng, Yongjun Li

  • June 3, 2026

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