Care Navigation for Methamphetamine Use Disorder: A Randomized Clinical Trial - Report - MDSpire
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Navigating Care for Individuals with Methamphetamine Use Disorder: Results from a Randomized Clinical Study

  • By

  • Alia Al-Tayyib

  • Deborah J. Rinehart

  • Karina G. Duarte

  • Aiden Gilbert

  • Chris Newton

  • Ryan Loh

  • Emily Bacon

  • Scott A. Simpson

  • September 2, 2026

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Clinical Report: Navigating Care for Individuals with Methamphetamine Use Disorder

Overview

This study evaluates a care navigation intervention incorporating contingency management principles for individuals with methamphetamine use disorder. The trial aims to determine its effectiveness in increasing treatment linkage following acute care encounters.

Background

Methamphetamine use disorder is a significant public health concern, contributing to rising mortality rates and various health complications. Current treatment options are limited, with no FDA-approved medications available for this disorder. Contingency management is identified as an effective psychosocial intervention for stimulant use disorders.

Data Highlights

No numerical data was provided in the source material.

Key Findings

  • The study utilized a randomized clinical trial design to compare usual care with a care navigation intervention.
  • Eligibility for the trial included adults with documented methamphetamine-related acute care encounters.
  • Contingency management is identified as the most effective psychosocial intervention for stimulant use disorders.
  • Less than 10% of addiction treatment programs implement contingency management.
  • The trial was conducted at Denver Health, which provides integrated behavioral health services.

Clinical Implications

The findings highlight the need for improved access to effective treatment strategies for methamphetamine use disorder. Implementing contingency management could enhance treatment engagement and retention among affected individuals.

Conclusion

This trial explores care navigation strategies for methamphetamine use disorder.

Related Resources & Content

  1. JAMA Psychiatry, 2026 -- Mirtazapine for Methamphetamine Use Disorder: A Randomized Clinical Trial
  2. Frontiers in Psychiatry, 2026 -- Navigating ‘k-land’: a qualitative exploration of participants’ experiences of ketamine-assisted psychotherapy for methamphetamine use disorder
  3. Open Forum Infectious Diseases, 2026 -- Project RETAIN: Enhancing Integrated Care for Cocaine-Using Individuals Living with HIV
  4. The ASAM/AAAP Clinical Practice Guideline on the Management of Stimulant Use Disorder
  5. BMC Psychiatry (Springer) — Cortical morphological alterations in methamphetamine-induced psychosis: a surface-based morphometry study
  6. FDA Guidance on Stimulant Use Disorders
  7. The ASAM/AAAP Clinical Practice Guideline on the Management of Stimulant Use Disorder
  8. Mirtazapine for Methamphetamine Use Disorder: A Randomized Clinical Trial | Trials | JAMA Psychiatry | JAMA Network
  9. Evaluating Reduced Use and Abstinence as Outcomes in Pharmacotherapy Trials for Stimulant Use Disorder: A Meta-Analysis of 12 Randomized Controlled Trials | Substance Use and Addiction Medicine | JAMA Psychiatry | JAMA Network
  10. Care Navigation for Methamphetamine Use Disorder: A Randomized Clinical Trial | Trials | JAMA Network Open | JAMA Network

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