Multidisciplinary treatment of follicular thyroid carcinoma with hepatic and pulmonary metastases: a case report and literature review - Report - MDSpire

Multidisciplinary treatment of follicular thyroid carcinoma with hepatic and pulmonary metastases: a case report and literature review

  • By

  • Zhongyao Wang

  • Tian Wen

  • Zixin Li

  • Jingdong Li

  • June 5, 2026

  • 0 min

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Clinical Report: Comprehensive Management of Follicular Thyroid Carcinoma

Overview

This report discusses a case of follicular thyroid carcinoma (FTC) with liver and lung metastases, emphasizing the importance of multidisciplinary treatment strategies. The patient underwent a robot-assisted hepatectomy followed by total thyroidectomy and radioactive iodine therapy.

Background

Follicular thyroid carcinoma is the second most common subtype of differentiated thyroid cancer, accounting for approximately 10% of cases. The management of distant metastases, particularly to rare sites such as the liver, poses significant clinical challenges.

Data Highlights

No numerical data or trial data presented in the article.

Key Findings

['A 56-year-old male developed FTC metastases to the liver and lungs 8 years post-surgery for FT-UMP.', 'Robot-assisted hepatectomy confirmed the diagnosis of FTC metastasis in the liver.', 'A comprehensive treatment plan included total thyroidectomy, radioactive iodine therapy, and active surveillance for lung metastases.', 'Follow-up at 12 months showed no signs of recurrence.', 'Multidisciplinary team collaboration was essential in formulating the treatment strategy.']

Clinical Implications

Continuous monitoring in patients with FT-UMP is crucial for early detection of potential metastasis.

Conclusion

This case highlights the complexities of managing FTC with distant metastases and the importance of tailored treatment strategies. Ongoing surveillance is crucial for early detection and intervention.

Related Resources & Content

  1. American Thyroid Association, 2025 ATA Guidelines -- Management Guidelines for Adult Patients with Differentiated Thyroid Cancer
  2. NCCN, Version 1.2025 -- NCCN Thyroid Carcinoma Guidelines
  3. Journal of Gastrointestinal Surgery — Management and Outcomes of Fibrolamellar Hepatocellular Carcinoma: A Comprehensive Review of Current Literature and Meta-Analysis
  4. Frontiers in Oncology — Complete radiographic response to immunotherapy in a patient with metastatic anaplastic thyroid cancer – a case report and review of the literature
  5. Frontiers in Oncology — Papillary thyroid carcinoma with brain and lung metastases: a case report
  6. Frontiers in Surgery — Diagnosis and treatment of breast cancer metastasis to thyroid: a case report and literature review
  7. 2025 American Thyroid Association Management Guidelines for Adult Patients with Differentiated Thyroid Cancer
  8. Version 1.2025
  9. Lenvatinib versus Placebo in Radioiodine-Refractory Thyroid Cancer | New England Journal of Medicine
  10. Cabozantinib for previously treated radioiodine‐refractory differentiated thyroid cancer: Updated results from the phase 3 COSMIC‐311 trial - PMC
  11. Genomic Considerations in the Treatment of Thyroid Carcinoma | JCO Oncology Practice
  12. Interventional Radiology Approaches for Liver Metastases from Thyroid Cancer: A Case Series and Overview of the Literature - PMC
  13. WHO 2022 updates on follicular cell and c-cell derived thyroid neoplasm - PMC
  14. Clinical Routine TERT Promoter Mutational Screening of Follicular Thyroid Tumors of Uncertain Malignant Potential (FT-UMPs): A Useful Predictor of Metastatic Disease - PMC
  15. Ultrasound and cytopathological characteristics of thyroid tumours of uncertain malignant potential - from diagnosis to treatment - PubMed

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