Clinical Report: Risk Assessment Model for Multiple Organ Dysfunction Syndrome in Patients with Wasp Stings
Overview
This study identifies key risk factors for multiple organ dysfunction syndrome (MODS) following wasp stings and develops a nomogram-based risk prediction model.
Background
Multiple organ dysfunction syndrome (MODS) is a severe complication that can arise from wasp stings, leading to high mortality rates. Early identification of patients at risk for MODS is critical for timely intervention.
Data Highlights
Parameter
MODS Group (n=90)
Non-MODS Group (n=234)
Age
Significantly higher
Lower
Time from sting to admission
Longer
Shorter
Pleural effusion
More common
Less common
RALE score
Higher
Lower
MPV/PLT
Higher
Lower
SIRI
Higher
Lower
Key Findings
Age, time to admission, pleural effusion, RALE score, MPV/PLT, and SIRI are independent risk factors for MODS (all P < 0.05).
The nomogram model achieved an AUC of 0.828 (95% CI: 0.776–0.880).
At the optimal cutoff of 0.368, the model's sensitivity was 66.7% and specificity was 87.9%.
Calibration curves indicated good agreement between predicted and observed outcomes.
Clinical Implications
The nomogram model provides a structured approach for assessing MODS risk in patients with wasp stings.
Conclusion
The study presents a risk assessment tool for MODS following wasp stings. Future research should focus on external validation of the nomogram model.
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