Adrenal cortical adenoma-cavernous hemangioma collision tumor: a case report - Report - MDSpire

Adrenal cortical adenoma-cavernous hemangioma collision tumor: a case report

  • By

  • Yanghong Ou

  • Lili Wang

  • Hongguang Qu

  • Yingmei Jia

  • May 22, 2026

  • 0 min

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Clinical Report: Collision Tumor of Adrenal Cortical Adenoma and Cavernous Hemangioma

Overview

This report presents a rare case of an adrenal collision tumor (ACT) comprising a cortical adenoma and a cavernous hemangioma in a 49-year-old woman. Imaging and pathological findings highlight the distinct characteristics of each tumor component, emphasizing the importance of accurate preoperative diagnosis.

Background

Adrenal collision tumors are uncommon and involve the coexistence of two distinct tumors within a single adrenal gland. Accurate diagnosis is essential for effective management and can influence treatment decisions, particularly when one component may represent metastatic disease. Imaging techniques such as CT and MRI are critical for identifying and characterizing these tumors.

Data Highlights

ComponentSize (cm)Volume PercentageCT Value (HU)
Cortical Adenoma2.5 x 2.0 x 1.835%-4.6 to -2.4
Cavernous Hemangioma4.0 x 3.5 x 3.065%Not specified

Key Findings

  • The patient was a 49-year-old woman with a three-year history of limb weakness.
  • Imaging revealed a well-defined right adrenal mass with two distinct tumor components.
  • The cortical adenoma was located laterally and accounted for approximately 35% of the total tumor volume.
  • The cavernous hemangioma was located medially, comprising about 65% of the total volume.
  • Distinct imaging characteristics were observed for each tumor component on CT and MRI.
  • Pathological examination confirmed the diagnosis of an adrenal collision tumor.

Clinical Implications

Recognizing the imaging patterns of different tumor components in adrenal masses is crucial for guiding clinical management. When atypical features are present, the possibility of an adrenal collision tumor should be considered to ensure appropriate diagnostic and therapeutic strategies.

Conclusion

This case illustrates the complexity of diagnosing adrenal collision tumors and the necessity for careful imaging evaluation. Accurate identification of tumor components can significantly impact clinical decision-making.

Related Resources & Content

  1. Olivero et al., Journal of Gastrointestinal Surgery, 2023 -- Minimally Invasive Surgical Approaches for Adrenocortical Carcinoma with Venous Invasion
  2. Frontiers in Oncology, 2026 -- Synchronous lung adenocarcinoma in situ and type B2-B3 thymoma in a frozen hemithorax: a case report and multidisciplinary approach
  3. Frontiers in Oncology, 2026 -- Case Report: Superficial Kaposiform Hemangioendothelioma Without the Kasabach–Merritt Phenomenon
  4. Endocrine, 2024 -- The diagnostic dilemma of adrenal vascular tumors: analysis of 21 cases and systematic review of the literature
  5. Frontiers, 2026 -- A rare case of adrenal collision tumor: Coexistence of cortical adenoma and cavernous hemangioma
  6. Journal of Gastrointestinal Surgery — Urgent Orthotopic Liver Transplantation Due to Hemorrhage from a Large Cavernous Hepatic Hemangioma: A Case Study and Literature Review
  7. Guideline-based evaluation of an adrenal mass
  8. The diagnostic dilemma of adrenal vascular tumors: analysis of 21 cases and systematic review of the literature | Endocrine | Springer Nature Link
  9. Frontiers | A rare case of adrenal collision tumor: Coexistence of cortical adenoma and cavernous hemangioma

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