Hypertension and frailty in older adults: a bibliometric analysis and knowledge mapping based on Web of Science, Scopus, and PubMed (1973–2025) - Report - MDSpire
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Hypertension and frailty in older adults: a bibliometric analysis and knowledge mapping based on Web of Science, Scopus, and PubMed (1973–2025)
Clinical Report: Exploring the Relationship Between Hypertension and Frailty
Overview
This bibliometric study analyzes the growing body of research on hypertension and frailty in older adults, revealing significant trends and knowledge structures. The findings highlight the increasing publication rates and key areas of focus within this field, particularly after 2015.
Background
Hypertension and frailty are prevalent in older adults, contributing to increased risks of adverse health outcomes such as falls and mortality. Understanding their relationship is crucial for developing effective management strategies in geriatric care. This study provides a comprehensive overview of the research landscape, which is essential for guiding future investigations and clinical practices.
Data Highlights
Database
Records Retrieved
Web of Science
1,853
Scopus
5,210
PubMed
1,615
Total Publications Included
4,954
Key Findings
Research on hypertension and frailty has accelerated significantly since 2015.
The United States contributed the highest number of publications (1,086; 21.9%).
Keyword analyses identified key areas such as hypertension management and frailty indices.
The PURE study and SPRINT trial were highlighted for their high citation impact.
Wang Y was identified as the most productive author in this research area.
Clinical Implications
Clinicians should be aware of the increasing prevalence of frailty among hypertensive older adults and the need for tailored management strategies. Future research should focus on multimorbid populations and validate interventions that address both blood pressure control and functional outcomes.
Conclusion
The study underscores the importance of understanding the interplay between hypertension and frailty, which is critical for improving health outcomes in older adults. Continued research in this area is essential for developing effective interventions.
Claims-based target trial emulation found no clear association between continued GLP-1 receptor agonist use in early pregnancy and nonlive birth, fetal growth abnormalities, or major congenital malformations.
