Development and internal validation of a nomogram for predicting short-term functional improvement after pharmacological treatment in severe symptomatic lumbar disk herniation - Report - MDSpire

Development and internal validation of a nomogram for predicting short-term functional improvement after pharmacological treatment in severe symptomatic lumbar disk herniation

  • By

  • Hanze Mao

  • Guangqi Lu

  • Shuaiqi Zhou

  • Minghui Zhuang

  • Xin Xiu

  • Jing Li

  • Xinyue Sun

  • Yakun Liu

  • Mingming Ma

  • Jiaming Hu

  • Jie Yu

  • Liguo Zhu

  • June 8, 2026

  • 0 min

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Clinical Report: Nomogram for Predicting Functional Improvement in LDH

Overview

{'add': 'Specify the pharmacological treatments compared.'}

Background

{'add': 'Discuss variability in treatment responses and implications.'}

Data Highlights

{'format': 'Ensure table format is consistent and clarify abbreviations.'}

Key Findings

{'add': 'Include specific statistical values for associations.'}

Clinical Implications

{'add': 'Discuss limitations of the nomogram.'}

Conclusion

{'add': 'Emphasize the need for external validation.'}

Related Resources & Content

  1. Frontiers in Surgery, 2026 -- Constructing a nomogram for forecasting incomplete clinical recovery following unilateral biportal endoscopy in lumbar disc herniation cases
  2. Springer, 2021 -- A Multicenter Analysis of a Prognostic Model for Complications and Deterioration Following Lumbar Microdiscectomy from the Norwegian Spine Surgery Registry
  3. Frontiers in Medicine, 2026 -- Rim enhancement on MRI predicts long-term outcomes in extruded/migrated lumbar disc herniation managed with an inflammation-preserving protocol: a 6-year prospective cohort study
  4. Frontiers in Surgery, 2026 -- Development and validation of a predictive nomogram for cage migration after posterior lumbar interbody fusion: a retrospective study of 517 patients
  5. NASS Guidelines on Lumbar Disk Herniation
  6. VA/DoD Guidelines for Low Back Pain
  7. Management of Low Back Pain: Guidelines From the VA/DoD
  8. Oral Steroids for Acute Radiculopathy Due to a Herniated Lumbar Disk: A Randomized Clinical Trial
  9. Epidural steroid injections in lumbar disc herniation: Evidence synthesis from 72 randomized controlled trials
  10. Intra-articular steroid injections for lumbar disk herniation: a systematic review and meta-analysis | Acta Neurochirurgica | Springer Nature Link
  11. Is platelet-rich plasma better than steroids as epidural drug of choice in lumbar disc disease with radiculopathy? Meta-analysis of randomized controlled trials - PMC
  12. Factors associated with improved outcomes after lumbar transforaminal epidural steroid injections for radicular pain: A systematic review - PMC
  13. Machine Learning Prediction of Therapeutic Outcome After Transforaminal Epidural Steroid Injection for Radiculopathy from Herniated Lumbar Disc - PMC
  14. Prediction of transforaminal epidural injection success in sciatica (POTEISS): a protocol for the development of a multivariable prediction model for outcome after transforaminal epidural steroid injection in patients with lumbar radicular pain due to disc herniation or stenosis - PMC
  15. Predictive factors for treatment success of transforaminal epidural steroid injection in lumbar disc herniation-induced sciatica - PMC

Original Source(s)

Development and internal validation of a nomogram for predicting short-term functional improvement after pharmacological treatment in severe symptomatic lumbar disk herniation

  • by Hanze Mao, Guangqi Lu, Shuaiqi Zhou, Minghui Zhuang, Xin Xiu, Jing Li, Xinyue Sun, Yakun Liu, Mingming Ma, Jiaming Hu, Jie Yu, Liguo Zhu

  • June 8, 2026

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