Waist-to-height ratio for OSA risk: a comparative analysis of NHANES and a clinical data - Report - MDSpire

Waist-to-height ratio for OSA risk: a comparative analysis of NHANES and a clinical data

  • By

  • Yajing Li

  • Jingjing Zhang

  • Xiaoyun Zhao

  • Yuechuan Li

  • May 29, 2026

  • 0 min

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Clinical Report: Evaluating the Association Between Waist-to-Height Ratio and OSA Risk

Overview

This study investigates the relationship between waist-to-height ratio (WHtR) and obstructive sleep apnea (OSA) risk using data from NHANES and clinical cases. Findings indicate that WHtR is a strong predictor of OSA risk, outperforming BMI in clinical settings.

Background

Obstructive sleep apnea (OSA) is a prevalent disorder with significant health implications, affecting millions globally. The rising prevalence of OSA, particularly in China, highlights the need for effective screening methods. Identifying reliable indicators of OSA risk, such as WHtR, is crucial for improving diagnosis and treatment rates.

Data Highlights

DatasetOR (95% CI)AUC
NHANES2.780 (2.536–3.048)0.727
Clinical11.998 (6.010–23.953)0.883

Key Findings

  • WHtR is positively associated with OSA risk in both NHANES and clinical datasets.
  • Each 0.1-unit increase in WHtR correlates with higher odds of OSA (NHANES: OR 2.780; clinical: OR 11.998).
  • RCS analysis indicates a significant non-linear relationship between WHtR and OSA risk.
  • WHtR outperforms BMI in predictive value for OSA in clinical settings.
  • Subgroup analyses show WHtR maintains predictive value across sex and age strata.

Clinical Implications

The findings suggest that WHtR could serve as a valuable screening tool for OSA, particularly in clinical populations. Healthcare providers may consider incorporating WHtR measurements into routine assessments for patients at risk of OSA.

Conclusion

WHtR is a strong indicator of OSA risk, demonstrating superior predictive value compared to BMI in clinical settings. This study supports the use of WHtR as a potential screening tool for OSA.

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