Publisher Correction: Metabolic septic shock sub-phenotypes, stability over time and association with clinical outcome - Report - MDSpire

Publisher Correction: Metabolic septic shock sub-phenotypes, stability over time and association with clinical outcome

  • By

  • David B. Antcliffe

  • Elsa Harte

  • Humma Hussain

  • Beatriz Jiménez

  • Charlotte Browning

  • Anthony C. Gordon

  • June 11, 2026

  • 0 min

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Correction Notice: Stability of Metabolic Septic Shock Sub-Phenotypes

Overview

This correction notice addresses the publication of incomplete figures and supplementary material in the original article regarding metabolic septic shock sub-phenotypes.

Background

Metabolic septic shock is a critical condition characterized by acute organ dysfunction due to a dysregulated response to infection.

Data Highlights

No numerical or trial data is presented in the correction notice.

Key Findings

  • The original article was updated to correct incomplete figures and supplementary material.
  • Metabolic sub-phenotypes can be identified across cohorts of patients with septic shock.
  • Sub-phenotype membership is dynamic over time, with certain profiles associated with higher mortality.
  • Circulating proteins provide insights into the pathophysiology of metabolic sub-phenotypes.

Clinical Implications

The correction emphasizes the importance of accurate data representation in clinical research.

Conclusion

This correction serves to clarify the findings of the original publication, reinforcing the significance of metabolic sub-phenotypes in septic shock and their relationship with clinical outcomes.

Related Resources & Content

  1. Intensive Care Medicine, 2025 -- Correction Notice: Stability of Metabolic Septic Shock Sub-Phenotypes Over Time and Their Relationship with Clinical Outcomes
  2. Intensive Care Medicine — Sub-phenotypes of Metabolic Septic Shock: Temporal Stability and Their Relationship with Clinical Outcomes
  3. Intensive Care Medicine — Evolving Endotypes of Sepsis: Are Fluctuations Indicative of Biological Progression? Response from the Author
  4. Infection — Longitudinal Analysis and Characterization of Sepsis Phenotypes Using Routine Clinical Data in Critically Ill Patients: A Retrospective Latent Profile Study
  5. JAMA Network Open — Multicenter Validation of Clinical Sepsis Phenotypes
  6. Metabolic septic shock sub-phenotypes, stability over time and association with clinical outcome | Intensive Care Medicine | Springer Nature Link
  7. Sepsis subphenotypes, theragnostics and personalized sepsis care | Intensive Care Medicine | Springer Nature Link
  8. Surviving Sepsis Campaign Adult Guidelines | SCCM
  9. VA ICME-D-25-00526V1.2
  10. Personalized Hemodynamic Resuscitation Targeting Capillary Refill Time in Early Septic Shock: The ANDROMEDA-SHOCK-2 Randomized Clinical Trial | Acid Base, Electrolytes, Fluids | JAMA | JAMA Network
  11. Early norepinephrine for patients with septic shock: an updated systematic review and meta-analysis with trial sequential analysis
  12. Effect of early adjunctive vasopressin initiation for septic shock patients: a target trial emulation | Critical Care | Springer Nature Link
  13. Scholars@Duke publication: Clinical Criteria for the Definition of Refractory Septic Shock: A Joint Delphi Consensus from the Society of Critical Care Medicine (SCCM) and European Society of Intensive Care Medicine (ESICM).

Original Source(s)

Publisher Correction: Metabolic septic shock sub-phenotypes, stability over time and association with clinical outcome

  • by David B. Antcliffe, Elsa Harte, Humma Hussain, Beatriz Jiménez, Charlotte Browning, Anthony C. Gordon

  • June 11, 2026

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